Product Name
Neurogenic protein big brain (bib), Recombinant Protein
Full Product Name
Recombinant Drosophila melanogaster Neurogenic protein big brain (bib)
Product Gene Name
bib recombinant protein
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Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
1-696aa; full length protein
Sequence
MADESLHTVP LEHNIDYHIV TLFERLEAMR KDSHGGGHGV NNRLSSTLQA PKRSMQAEIR TLEFWRSIIS ECLASFMYVF IVCGAAAGVG VGASVSSVLL ATALASGLAM ATLTQCFLHI SGAHINPAVT LALCVVRSIS PIRAAMYITA QCGGGIAGAA LLYGVTVPGY QGNLQAAISH SAALAAWERF GVEFILTFLV VLCYFVSTDP MKKFMGNSAA SIGCAYSACC FVSMPYLNPA RSLGPSFVLN KWDSHWVYWF GPLVGGMASG LVYEYIFNSR NRNLRHNKGS IDNDSSSIHS EDELNYDMDM EKPNKYQQSQ GTYPRGQSNG NGGGQAAGNG QHQAANMGQM PGVVANAGQG NYCQNLYTAP PLSSKYDQQQ EPLYGGTRSL YCRSPTLTRS NLNRSQSVYA KSNTAINRDI VPRPGPLVPA QSLYPMRTQQ QQQQQQQQQQ QVAPAPQSSH LQNQNVQNQM QQRSESIYGM RGSMRGQQQP IQQQQQQQQQ QQLQQQQPNM GVQQQQMQPP PQMMSDPQQQ PQGFQPVYGT RTNPTPMDGN HKYDRRDPQQ MYGVTGPRNR GQSAQSDDSS YGSYHGSAVT PPARHPSVEP SPPPPPMLMY APPPQPNAAH PQPIRTQSER KVSAPVVVSQ PAACAVTYTT SQGSAVTAQQ QQQQQQQQQQ QQQQQQQQMM MQQQQQHYGM LPLRPN
3D Structure
ModBase 3D Structure for P23645
Host
Cell Free Expression
Form/Format
Liquid containing glycerol
Species
Drosophila melanogaster (Fruit fly)
Storage Buffer
Tris-based buffer, 50% glycerol.
Preparation and Storage
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
Repeated freezing and thawing is not recommended. Store working aliquots at 4 degree C for up to one week.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of bib recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Product Categories/Family for bib recombinant protein
Transmembrane Protein
Application Notes for bib recombinant protein
This is a recombinant transmembrane protein expressed in a cell-free expression system.
NCBI/Uniprot data below describe general gene information for bib. It may not necessarily be applicable to this product.
NCBI Accession #
NP_476837.1
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NCBI GenBank Nucleotide #
NM_057489.5
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UniProt Primary Accession #
P23645
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UniProt Secondary Accession #
Q9VL53[Other Products]
UniProt Related Accession #
P23645[Other Products]
Molecular Weight
76,509 Da
NCBI Official Full Name
big brain, isoform A
NCBI Official Synonym Full Names
big brain
NCBI Official Symbol
bib??[Similar Products]
NCBI Official Synonym Symbols
Bib; BIB_DROME; CG4722; DmelCG4722; EP(2)2278; l(2)neo66; l(2)neo91; m-bib
??[Similar Products]
NCBI Protein Information
CG4722 gene product from transcript CG4722-RA
UniProt Protein Name
Neurogenic protein big brain
Protein Family
Neurogenic protein big brain
UniProt Gene Name
bib??[Similar Products]
UniProt Entry Name
BIB_DROME
UniProt Comments for bib
Essential for proper differentiation of ectoderm. Acts synergistically with neurogenic locus proteins Notch and Delta during the separation of neural and epidermal cell lineages in response to the lateral inhibition signal. Voltage-insensitive monovalent cation channel. Ion transport is blocked by the presence of divalent cations.
Research Articles on bib
1. Bib-transfected L cells formed aggregated clusters, while control-L cells remained as a single cell suspension. Ion permeation was not confirmed in L cells stably expressing Bib.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
