Product Name
3-ketoacyl-CoA thiolase, peroxisomal (ACAA1), Polyclonal Antibody
Full Product Name
Rabbit anti-human 3-ketoacyl-CoA thiolase, peroxisomal polyclonal Antibody(ACAA1)
Product Synonym Names
Acetyl-CoA acyltransferase; Beta-ketothiolase; Peroxisomal 3-oxoacyl-CoA thiolase; ACAA; PTHIO; ACAA1
Product Gene Name
anti-ACAA1 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for P09110
Purity/Purification
Caprylic Acid Ammonium Sulfate Precipitation purified
Immunogen
Recombinant human 3-ketoacyl-CoA thiolase, peroxisomal protein(27-331AA)
Conjugation
Non-conjugated
Storage Buffer
Preservative: 0.03% Proclin 300; Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-99258
Preparation and Storage
Shipped at 4 degree C. Upon delivery, aliquot and store at -20 degree C or -80 degree C.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of anti-ACAA1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-ACAA1 antibody
ELISA (EIA), Immunohistochemistry (IHC)
Application Notes for anti-ACAA1 antibody
Recommended dilution: IHC: 1:20-1:200
Immunohistochemistry (IHC) of anti-ACAA1 antibody
Immunohistochemistry of paraffin-embedded human thyroid tissue
gland using MBS7005224 at dilution 1:100
Immunohistochemistry (IHC) of anti-ACAA1 antibody
Immunohistochemistry of paraffin-embedded human prostate cancer gland using MBS7005224 at dilution 1:100
NCBI/Uniprot data below describe general gene information for ACAA1. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001123882.1
[Other Products]
NCBI GenBank Nucleotide #
NM_001130410.1
[Other Products]
UniProt Primary Accession #
P09110
[Other Products]
UniProt Secondary Accession #
Q96CA6; G5E935[Other Products]
UniProt Related Accession #
P09110[Other Products]
Molecular Weight
34,665 Da[Similar Products]
NCBI Official Full Name
3-ketoacyl-CoA thiolase, peroxisomal isoform b
NCBI Official Synonym Full Names
acetyl-CoA acyltransferase 1
NCBI Official Symbol
ACAA1??[Similar Products]
NCBI Official Synonym Symbols
ACAA; THIO; PTHIO
??[Similar Products]
NCBI Protein Information
3-ketoacyl-CoA thiolase, peroxisomal
UniProt Protein Name
3-ketoacyl-CoA thiolase, peroxisomal
UniProt Synonym Protein Names
Acetyl-CoA acyltransferase; Beta-ketothiolase; Peroxisomal 3-oxoacyl-CoA thiolase
Protein Family
3-ketoacyl-CoA thiolase
UniProt Gene Name
ACAA1??[Similar Products]
UniProt Synonym Gene Names
ACAA; PTHIO??[Similar Products]
UniProt Entry Name
THIK_HUMAN
NCBI Summary for ACAA1
This gene encodes an enzyme operative in the beta-oxidation system of the peroxisomes. Deficiency of this enzyme leads to pseudo-Zellweger syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008]
UniProt Comments for ACAA1
ACAA1: an enzyme operative in the beta-oxidation system of the peroxisomes. Deficiency of this enzyme leads to pseudo-Zellweger syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008]
Protein type: EC 2.3.1.16; Lipid Metabolism - fatty acid; Acetyltransferase; Amino Acid Metabolism - valine, leucine and isoleucine degradation; Lipid Metabolism - unsaturated fatty acid biosynthesis
Chromosomal Location of Human Ortholog: 3p22.2
Cellular Component: intracellular membrane-bound organelle; membrane; peroxisomal matrix; peroxisome
Molecular Function: acetyl-CoA C-acyltransferase activity; palmitoyl-CoA oxidase activity; protein binding
Biological Process: bile acid metabolic process; cellular lipid metabolic process; fatty acid beta-oxidation; fatty acid beta-oxidation using acyl-CoA oxidase; unsaturated fatty acid metabolic process; very-long-chain fatty acid metabolic process
Disease: D-bifunctional Protein Deficiency
Research Articles on ACAA1
1. Findings suggest that protective effects of endotoxin exposure on asthma may vary depending upon the presence or absence of a polymorphism in ACAA1.
Precautions
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Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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