Full Product Name
MTMR2 Antibody, Biotin conjugated
Product Synonym Names
Myotubularin-related protein 2; Phosphatidylinositol-3; 5-bisphosphate 3-phosphatase; MTMR2; KIAA1073
Product Gene Name
anti-MTMR2 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q13614
Purity/Purification
>95%, Protein G purified
Immunogen
Recombinant Human Myotubularin-related protein 2 protein (1-173AA)
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Preparation and Storage
Upon receipt, store at -20 degree C or -80 degree C. Avoid repeated freeze.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of anti-MTMR2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-MTMR2 antibody
Phosphatase that acts on lipids with a phosphoinositol headgroup. Has phosphatase activity towards phosphatidylinositol 3-phosphate and phosphatidylinositol 3, 5-bisphosphate.
Product Categories/Family for anti-MTMR2 antibody
Neuroscience; Signal transduction
Applications Tested/Suitable for anti-MTMR2 antibody
ELISA (EIA)
NCBI/Uniprot data below describe general gene information for MTMR2. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001230500.1
[Other Products]
NCBI GenBank Nucleotide #
NM_001243571.1
[Other Products]
UniProt Primary Accession #
Q13614
[Other Products]
UniProt Secondary Accession #
Q9UPS9; A6NN98[Other Products]
UniProt Related Accession #
Q13614[Other Products]
Molecular Weight
65,959 Da
NCBI Official Full Name
myotubularin-related protein 2 isoform 2
NCBI Official Synonym Full Names
myotubularin related protein 2
NCBI Official Symbol
MTMR2??[Similar Products]
NCBI Official Synonym Symbols
CMT4B; CMT4B1
??[Similar Products]
NCBI Protein Information
myotubularin-related protein 2
UniProt Protein Name
Myotubularin-related protein 2
UniProt Synonym Protein Names
Phosphatidylinositol-3,5-bisphosphate 3-phosphatase (EC:3.1.3.95
Protein Family
Myotubularin-related protein
UniProt Gene Name
MTMR2??[Similar Products]
UniProt Synonym Gene Names
KIAA1073??[Similar Products]
NCBI Summary for MTMR2
This gene is a member of the myotubularin family of phosphoinositide lipid phosphatases. The encoded protein possesses phosphatase activity towards phosphatidylinositol-3-phosphate and phosphatidylinositol-3,5-bisphosphate. Mutations in this gene are a cause of Charcot-Marie-Tooth disease type 4B, an autosomal recessive demyelinating neuropathy. Alternatively spliced transcript variants encoding multiple isoforms have been found for this gene. [provided by RefSeq, Aug 2011]
UniProt Comments for MTMR2
Phosphatase that acts on lipids with a phosphoinositol headgroup. Has phosphatase activity towards phosphatidylinositol 3-phosphate and phosphatidylinositol 3,5-bisphosphate.
Research Articles on MTMR2
1. Expression of several MTMR2 isoforms ameliorates the myopathic phenotype owing to MTM1 loss, with increased muscle force, reduced myofiber atrophy, and reduction of the intracellular disorganization hallmarks associated with myotubular myopathy.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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