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Pituitary-specific positive transcription factor 1 (Pou1f1), Recombinant Protei

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產(chǎn)品名稱: Pituitary-specific positive transcription factor 1 (Pou1f1), Recombinant Protei
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Pituitary-specific positive transcription factor 1 (Pou1f1), Recombinant Protein


Pituitary-specific positive transcription factor 1 (Pou1f1), Recombinant Protei  的詳細(xì)介紹
Product Name

Pituitary-specific positive transcription factor 1 (Pou1f1), Recombinant Protein

Full Product Name

Recombinant Mouse Pituitary-specific positive transcription factor 1 (Pou1f1)

Product Gene Name

Pou1f1 recombinant protein

[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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Sequence Positions
1-291aa, Full length protein
Sequence
MSCQSFTSAD TFITLNSDAS AALPLRMHHS AAECLPASNH ATNVMSTATG LHYSVPSCHY GNQPSTYGVM AGSLTPCLYK FPDHTLSHGF PPLHQPLLAE DPAASEFKQE LRRKSKLVEE PIDMDSPEIR ELEQFANEFK VRRIKLGYTQ TNVGEALAAV HGSEFSQTTI CRFENLQLSF KNACKLKAIL SKWLEEAEQV GALYNEKVGA NERKRKRRTT ISVAAKDALE RHFGEHSKPS SQEIMRMAEE LNLEKEVVRV WFCNRRQREK RVKTSLNQSL FSISKEHLEC R
3D Structure
ModBase 3D Structure for Q00286
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Species
Mouse
Storage Buffer
Tris-based buffer, 50% glycerol
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of Pou1f1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for
Pou1f1 recombinant protein
This gene encodes a member of the POU family of transcription factors that regulate mammalian development. The protein regulates expression of several genes involved in pituitary development and hormone expression. Mutations in this genes result in combined pituitary hormone deficiency. Multiple transcript variants encoding different isoforms have been found for this gene.
NCBI/Uniprot data below describe general gene information for Pou1f1. It may not necessarily be applicable to this product.
NCBI GI #
6679335
NCBI GeneID
18736
NCBI Accession #
NP_032875.1 [Other Products]
NCBI GenBank Nucleotide #
NM_008849.4 [Other Products]
UniProt Primary Accession #
Q00286 [Other Products]
UniProt Related Accession #
Q00286[Other Products]
Molecular Weight
35,752 Da
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NCBI Official Full Name
pituitary-specific positive transcription factor 1
NCBI Official Synonym Full Names
POU domain, class 1, transcription factor 1
NCBI Official Symbol
Pou1f1??[Similar Products]
NCBI Official Synonym Symbols
dw; Hmp1; Pit1; GHF-1; Pit-1; dwarf; Pit1-rs1
??[Similar Products]
NCBI Protein Information
pituitary-specific positive transcription factor 1
UniProt Protein Name
Pituitary-specific positive transcription factor 1
UniProt Synonym Protein Names
Growth hormone factor 1; GHF-1
Protein Family
Pituitary-specific positive transcription factor
UniProt Gene Name
Pou1f1??[Similar Products]
UniProt Synonym Gene Names
Pit-1; Pit1; PIT-1; GHF-1??[Similar Products]
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UniProt Comments for Pou1f1
Transcription factor involved in the specification of the lactotrope, somatotrope, and thyrotrope phenotypes in the developing anterior pituitary. Activates growth hormone and prolactin genes. Specifically binds to the consensus sequence 5'-TAAAT-3'.
Research Articles on Pou1f1
1. Pit1 deletion inhibited USP7/IRS1 dissociation upon insulin stimulation.
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Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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