Product Name
4-Hydroxyphenylpyruvate Dioxygenase (mHPD), Recombinant Protein
Full Product Name
Recombinant Mouse 4-Hydroxyphenylpyruvate Dioxygenase
Product Gene Name
mHPD recombinant protein
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Other Notes
Small volumes of mHPD recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Product Categories/Family for mHPD recombinant protein
ENZYMES
NCBI/Uniprot data below describe general gene information for mHPD. It may not necessarily be applicable to this product.
NCBI Accession #
AAC73008.1
[Other Products]
UniProt Secondary Accession #
Q13234; A8K461; B3KQ63[Other Products]
UniProt Related Accession #
P32754[Other Products]
Molecular Weight
40,497 Da
NCBI Official Full Name
4-hydroxyphenylpyruvate-dioxygenase
NCBI Official Synonym Full Names
4-hydroxyphenylpyruvate dioxygenase
NCBI Official Symbol
HPD??[Similar Products]
NCBI Official Synonym Symbols
PPD; 4HPPD; GLOD3; 4-HPPD; HPPDASE
??[Similar Products]
NCBI Protein Information
4-hydroxyphenylpyruvate dioxygenase
UniProt Protein Name
4-hydroxyphenylpyruvate dioxygenase
UniProt Synonym Protein Names
4-hydroxyphenylpyruvic acid oxidase; 4HPPD; HPD; HPPDase
Protein Family
4-hydroxyphenylpyruvate dioxygenase
UniProt Gene Name
HPD??[Similar Products]
UniProt Synonym Gene Names
PPD; 4HPPD; HPD; HPPDase??[Similar Products]
NCBI Summary for mHPD
The protein encoded by this gene is an enzyme in the catabolic pathway of tyrosine. The encoded protein catalyzes the conversion of 4-hydroxyphenylpyruvate to homogentisate. Defects in this gene are a cause of tyrosinemia type 3 (TYRO3) and hawkinsinuria (HAWK). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2010]
UniProt Comments for mHPD
Key enzyme in the degradation of tyrosine.
Research Articles on mHPD
1. The mutagenesis and structural simulation studies demonstrate the critical and unique role of each ligand in the function of HPPD, and which correlates with their respective co-ordination position.
Precautions
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Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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