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TREM-2, Recombinant Protein

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產(chǎn)品名稱: TREM-2, Recombinant Protein
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簡單介紹

TREM-2, Recombinant Protein


TREM-2, Recombinant Protein  的詳細介紹
Product Name

TREM-2, Recombinant Protein

Full Product Name

Recombinant Human TREM-2 Protein

Product Synonym Names
TREM2; Triggering receptor expressed on myeloid cells 2; TREM-2; Triggering receptor expressed on monocytes 2; TREM2
Product Gene Name

TREM-2 recombinant protein

[Similar Products]
Product Synonym Gene Name
TREM2[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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Sequence
HNTTVFQGVA GQSLQVSCPY DSMKHWGRRK AWCRQLGEKG PCQRVVSTHN LWLLSFLRRW NGSTAITDDT LGGTLTITLR NLQPHDAGLY QCQSLHGSEA DTLRKVLVEV LADPLDHRDA GDLWFPGESE SFEDAHVEHS ISRSLLEGEI PFPPTS
3D Structure
ModBase 3D Structure for Q9NZC2
Host
Human Cells
Purity/Purification
> 95% by SDS-PAGE.
Form/Format
Lyophilized from a 0.2 muM filtered solution of PBS, pH 7.4.
Species
Human
Endotoxin
< 1 EU/mug of the protein by LAL method.
Tag
6xHis tag at the C-terminus
Reconstitution
Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water.
Protein Construction
High quality, high purity and low endotoxin recombinant Recombinant Human TREM-2 Protein (RP00866), tested reactivity in Human and has been validated in SDS-PAGE.100% guaranteed.
Preparation and Storage
Store the lyophilized protein at-20 degree C to-80 degree C for long term.
After reconstitution, the protein solution is stable at-20 degree C for 3 months, at 2-8 degree C for up to 1 week.
Other Notes
Small volumes of TREM-2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for
TREM-2 recombinant protein
Recombinant Human TREM-2 Protein is produced by human cells expression system. The target protein is expressed with sequence (His19-Ser174) of human TREM-2 (Accession #Q9NZC2) fused with a 6xHis tag at the C-terminus.

SDS-Page of TREM-2 recombinant protein
Recombinant Human TREM-2 Protein was determined by SDS-PAGE under reducing conditions with Coomassie Blue.
TREM-2 recombinant protein SDS-Page image
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NCBI/Uniprot data below describe general gene information for TREM-2. It may not necessarily be applicable to this product.
NCBI GI #
425876764
NCBI GeneID
54209
NCBI Accession #
NP_001258750.1 [Other Products]
NCBI GenBank Nucleotide #
NM_001271821.1 [Other Products]
UniProt Primary Accession #
Q9NZC2 [Other Products]
UniProt Secondary Accession #
Q8N5H8; Q8WYN6[Other Products]
UniProt Related Accession #
Q9NZC2[Other Products]
Molecular Weight
24,328 Da
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NCBI Official Full Name
triggering receptor expressed on myeloid cells 2 isoform 2
NCBI Official Synonym Full Names
triggering receptor expressed on myeloid cells 2
NCBI Official Symbol
TREM2??[Similar Products]
NCBI Official Synonym Symbols
PLOSL2; TREM-2; Trem2a; Trem2b; Trem2c
??[Similar Products]
NCBI Protein Information
triggering receptor expressed on myeloid cells 2
UniProt Protein Name
Triggering receptor expressed on myeloid cells 2
UniProt Synonym Protein Names
Triggering receptor expressed on monocytes 2
UniProt Gene Name
TREM2??[Similar Products]
UniProt Synonym Gene Names
TREM-2??[Similar Products]
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NCBI Summary for TREM-2
This gene encodes a membrane protein that forms a receptor signaling complex with the TYRO protein tyrosine kinase binding protein. The encoded protein functions in immune response and may be involved in chronic inflammation by triggering the production of constitutive inflammatory cytokines. Defects in this gene are a cause of polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Nov 2012]
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UniProt Comments for TREM-2
Forms a receptor signaling complex with TYROBP and triggers activation of the immune responses in macrophages and dendritic cells. May have a role in chronic inflammations and may stimulate production of constitutive rather than inflammatory chemokines and cytokines.
Research Articles on TREM-2
1. Our data establish a critical link between oAbeta1-42, a major pathological component of Alzheimer's disease and TREM2
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Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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