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3-phosphoinositide dependent protein kinase-1, ELISA Kit

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產(chǎn)品名稱: 3-phosphoinositide dependent protein kinase-1, ELISA Kit
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3-phosphoinositide dependent protein kinase-1, ELISA Kit


3-phosphoinositide dependent protein kinase-1, ELISA Kit  的詳細(xì)介紹
Product Name

3-phosphoinositide dependent protein kinase-1 (PDPK1), ELISA Kit

Full Product Name

Mouse 3-phosphoinositide-dependent protein kinase 1, PDPK1 ELISA Kit

Product Synonym Names
Mouse 3-phosphoinositide-dependent protein kinase 1 (PDPK1) ELISA kit; MGC20087; MGC35290; PDK1; PRO0461; PkB kinase like gene 1; PkB-like 1; protein kinase; 3-phosphoinositide dependent protein kinase-1
Product Gene Name

PDPK1 elisa kit

[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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Request for Current Manual Insert
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3D Structure
ModBase 3D Structure for Q9Z2A0
Species Reactivity
Mouse
Preparation and Storage
Store all reagents at 2-8 degree C
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
Other Notes
Small volumes of PDPK1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms for PDPK1 purchase
MBS9336734 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the 3-phosphoinositide dependent protein kinase-1 (PDPK1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing PDPK1. The ELISA analytical biochemical technique of the MBS9336734 kit is based on PDPK1 antibody-PDPK1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect PDPK1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, PDPK1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for PDPK1. It may not necessarily be applicable to this product.
NCBI GI #
124107594
NCBI GeneID
18607
NCBI Accession #
NP_035192.2 [Other Products]
NCBI GenBank Nucleotide #
NM_011062.4 [Other Products]
UniProt Primary Accession #
Q9Z2A0 [Other Products]
UniProt Secondary Accession #
Q9R1D8; Q9R215; A6H6U3[Other Products]
UniProt Related Accession #
Q9Z2A0[Other Products]
Molecular Weight
63,759 Da
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NCBI Official Full Name
3-phosphoinositide-dependent protein kinase 1 isoform A
NCBI Official Synonym Full Names
3-phosphoinositide dependent protein kinase 1
NCBI Official Symbol
Pdpk1??[Similar Products]
NCBI Official Synonym Symbols
Pdk1
??[Similar Products]
NCBI Protein Information
3-phosphoinositide-dependent protein kinase 1; mPDK1; Pkb kinase; 3-phosphoinositide dependent protein kinase-1
UniProt Protein Name
3-phosphoinositide-dependent protein kinase 1
Protein Family
3-phosphoinositide-dependent protein kinase
UniProt Gene Name
Pdpk1??[Similar Products]
UniProt Synonym Gene Names
Pdk1; mPDK1??[Similar Products]
UniProt Entry Name
PDPK1_MOUSE
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UniProt Comments for PDPK1
PDK1: an AGC kinase of the PKB family that contains a PH domain. Involved in a wide variety of processes including cell proliferation, differentiation and apoptosis. Autophosphorylation in the activation loop is necessary for activity. Phosphorylates and activates kinases including Akt, PKC isozymes, p70 S6K and RSK. Three alternatively-spliced isoforms have been described.

Protein type: Kinase, protein; Protein kinase, AGC; Nuclear receptor co-regulator; EC 2.7.11.1; Protein kinase, Ser/Thr (non-receptor); AGC group; PKB family

Cellular Component: cell projection; membrane; cytoplasmic membrane-bound vesicle; cytoplasm; plasma membrane; cytosol; cell junction; nucleus

Molecular Function: transferase activity; protein serine/threonine kinase activity; protein binding; phospholipase binding; 3-phosphoinositide-dependent protein kinase activity; transferase activity, transferring phosphorus-containing groups; nucleotide binding; kinase activity; protein kinase binding; insulin receptor binding; ATP binding; protein kinase activity; phospholipase activator activity

Biological Process: regulation of mast cell degranulation; focal adhesion formation; epidermal growth factor receptor signaling pathway; cell migration; transcription, DNA-dependent; activation of protein kinase B; peptidyl-threonine phosphorylation; calcium-mediated signaling; signal transduction; protein amino acid phosphorylation; hyperosmotic response; cellular response to insulin stimulus; regulation of transcription, DNA-dependent; negative regulation of toll-like receptor signaling pathway; negative regulation of protein kinase activity; positive regulation of release of sequestered calcium ion into cytosol; regulation of I-kappaB kinase/NF-kappaB cascade; negative regulation of transforming growth factor beta receptor signaling pathway; phosphorylation
Research Articles on PDPK1
1. These results demonstrated that PDK1 and mTORC2 synergistically promote postnatal heart growth and maintain heart function in postnatal mice.
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Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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