Full Product Name
NLRP7 Antibody (Rabbit Polyclonal)
Product Gene Name
anti-NLRP7 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Species Reactivity
Human
Predicted: Mouse, Rat
Form/Format
Purified by protein affinity column containing 1% BSA and 0.02% NaN3
Preparation and Storage
Already reconstituted in 200ul sterile H2O. The antibody is stable for at least one year when stored at-20 degree C after reconstitution. Avoid repeated freeze/defrost cycles.
Other Notes
Small volumes of anti-NLRP7 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-NLRP7 antibody
Rabbit polyclonal NLRP7 (1) antibody was raised against a recombinate human NLRP7 protein 459-705aa (BC109125).
Applications Tested/Suitable for anti-NLRP7 antibody
ELISA (EIA), Western Blot (WB)
Application Notes for anti-NLRP7 antibody
ELISA: 1:20,000-1:80,000
WB: 1:200-1:1,000
NCBI/Uniprot data below describe general gene information for NLRP7. It may not necessarily be applicable to this product.
NCBI Accession #
BC109125
[Other Products]
UniProt Secondary Accession #
Q32MH8; Q7RTR1; E9PE16[Other Products]
UniProt Related Accession #
Q8WX94[Other Products]
Molecular Weight
118,303 Da
NCBI Official Full Name
Homo sapiens NLR family, pyrin domain containing 7, mRNA
NCBI Official Synonym Full Names
NLR family pyrin domain containing 7
NCBI Official Symbol
NLRP7??[Similar Products]
NCBI Official Synonym Symbols
HYDM; PAN7; NALP7; NOD12; PYPAF3; CLR19.4
??[Similar Products]
NCBI Protein Information
NACHT, LRR and PYD domains-containing protein 7
UniProt Protein Name
NACHT, LRR and PYD domains-containing protein 7
UniProt Synonym Protein Names
Nucleotide-binding oligomerization domain protein 12; PYRIN-containing APAF1-like protein 3
Protein Family
NACHT, LRR and PYD domains-containing protein
UniProt Gene Name
NLRP7??[Similar Products]
UniProt Synonym Gene Names
NALP7; NOD12; PYPAF3??[Similar Products]
NCBI Summary for NLRP7
This gene encodes a member of the NACHT, leucine rich repeat, and PYD containing (NLRP) protein family. It has an N-terminal pyrin domain, followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. NLRP proteins are implicated in the activation of proinflammatory caspases through multiprotein complexes called inflammasomes. This gene may act as a feedback regulator of caspase-1-dependent interleukin 1-beta secretion. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
UniProt Comments for NLRP7
Inhibits CASP1/caspase-1-dependent IL1B secretion.
Research Articles on NLRP7
1. Maternal heterozygous nonsense deletion in NLRP7 leads to recurrent reproductive failure and DNA methylation disturbances in the offspring.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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