Product Name
5, 10methylenetetrahydrafolatereductase (MTHFR), ELISA Kit
Full Product Name
Human 5, 10methylenetetrahydrafolatereductase (MTHFR) ELISA Kit
Product Gene Name
MTHFR elisa kit
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sample Manual Insert
Download Sample PDF Manual View Sample PDF Manual
Request for Current Manual Insert
Request Current Manual
3D Structure
ModBase 3D Structure for P42898
Preparation and Storage
Store at 2 to 8 degree C for 6 months.
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
Other Notes
Small volumes of MTHFR elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms for MTHFR purchase
MBS163979 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the 5, 10methylenetetrahydrafolatereductase (MTHFR) ELISA Kit target analytes in
biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing MTHFR. The ELISA analytical biochemical technique of the MBS163979 kit is based on MTHFR antibody-MTHFR antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect MTHFR antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, MTHFR. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
NCBI/Uniprot data below describe general gene information for MTHFR. It may not necessarily be applicable to this product.
NCBI Accession #
NP_005948.3
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NCBI GenBank Nucleotide #
NM_005957.4
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UniProt Primary Accession #
P42898
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UniProt Secondary Accession #
Q5SNW6; Q5SNW9; Q7Z6M6; Q8IU73; Q9UQR2; B2R7A6[Other Products]
UniProt Related Accession #
P42898[Other Products]
Molecular Weight
78,965 Da
NCBI Official Full Name
methylenetetrahydrofolate reductase isoform 2
NCBI Official Synonym Full Names
methylenetetrahydrofolate reductase
NCBI Official Symbol
MTHFR??[Similar Products]
NCBI Protein Information
methylenetetrahydrofolate reductase
UniProt Protein Name
Methylenetetrahydrofolate reductase
Protein Family
Methylenetetrahydrofolate reductase
UniProt Gene Name
MTHFR??[Similar Products]
NCBI Summary for MTHFR
The protein encoded by this gene catalyzes the conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a co-substrate for homocysteine remethylation to methionine. Genetic variation in this gene influences susceptibility to occlusive vascular disease, neural tube defects, colon cancer and acute leukemia, and mutations in this gene are associated with methylenetetrahydrofolate reductase deficiency.[provided by RefSeq, Oct 2009]
UniProt Comments for MTHFR
Catalyzes the conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a co-substrate for homocysteine remethylation to methionine.
Research Articles on MTHFR
1. C polymorphism and, altered homocysteine and vitamin B12 levels might play a vital role in the precipitation of vitiligo.">MTHFR 1298 A>C polymorphism and, altered homocysteine and vitamin B12 levels might play a vital role in the precipitation of vitiligo.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.