Product Name
Collagen Type VI (COL6A1), Polyclonal Antibody
Full Product Name
Rabbit anti Collagen Type VI
Product Synonym Names
Rabbit Antibody to Human Collagen Type VI
Product Gene Name
anti-COL6A1 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Chromosome Location
Chromosome: 21; NC_000021.8 (47401663..47424963). Location: 21q22.3
3D Structure
ModBase 3D Structure for P12109
Specificity
Collagen Type VI
Minimum cross-reaction to Type I, II, III, IV, and V Collagens. Typically <1% cross reactivity against other types of collagens was detected by ELISA against purified standards. Some class specific anti-collagens may be specific for th
Purity/Purification
Immunoaffinity chromatography using immobilized antigens followed by extensive cross-adsorption against other collagens, human serum proteins and non-collagen extracellular matrix proteins to remove any unwanted specificities.
Form/Format
Affinity Purified, Liquid
Concentration
1mg/ml (OD280nm) (lot specific)
Immunogen
Collagen Type VI from human and bovine placenta
Buffer
0.125M Sodium Borate, 0.075M Sodium Chloride, 0.005M EDTA, pH 8.0.
Preservative
0.01% (w/v) Sodium Azide
Important Note
Centrifuge before opening to ensure complete recovery of vial contents.
Warnings
This product contains sodium azide, which has been classified as Xn (Harmful), in European Directive 67/548/EEC in the concentration range of 0.1 - 1.0 %. When disposing of this reagent through lead or copper plumbing, flush with copious volumes of water to prevent azide build-up in drains.
Preparation and Storage
Store at 2 to 8 degree C before opening. This product is stable at 2 to 8 degree C as an undiluted liquid. Prepare working dilution only prior to immediate use. For extended storage mix with an equal volume of glycerol, aliquot and store at -20 degree C o
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of anti-COL6A1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Product Categories/Family for anti-COL6A1 antibody
Polyclonal Antibodies to Collagens and Extracellular Matrix Proteins
Applications Tested/Suitable for anti-COL6A1 antibody
EIA/ELISA, Immunoblot, Immunohistochemistry - Formalin
Application Notes for anti-COL6A1 antibody
Have been used for indirect trapping ELISA for quantitation of antigen in serum using a standard curve and for non-denaturing immunoblot for highly sensitive qualitative analysis. This product was assayed by non-denaturing immunoblot and found to be react
NCBI/Uniprot data below describe general gene information for COL6A1. It may not necessarily be applicable to this product.
UniProt Primary Accession #
P12109
[Other Products]
UniProt Secondary Accession #
O00117; O00118; Q14040; Q14041; Q16258; Q7Z645; Q9BSA8[Other Products]
UniProt Related Accession #
P12109; Q05BT9; Q8TBN2[Other Products]
Molecular Weight
108,529 Da[Similar Products]
NCBI Official Full Name
collagen, type VI, alpha 1, isoform CRA_b
NCBI Official Synonym Full Names
collagen, type VI, alpha 1
NCBI Official Symbol
COL6A1??[Similar Products]
NCBI Official Synonym Symbols
OPLL
??[Similar Products]
NCBI Protein Information
collagen alpha-1(VI) chain; collagen alpha-1(VI) chain; OTTHUMP00000115501; alpha 1 (VI) chain (61 AA); collagen VI, alpha-1 polypeptide
UniProt Protein Name
Collagen alpha-1(VI) chain
UniProt Gene Name
COL6A1??[Similar Products]
UniProt Entry Name
CO6A1_HUMAN
Product References and Citations for anti-COL6A1 antibody
??Puolakkainen, P.A., et al., (2004), "Enhanced growth of pancreatic tumors in SPARC-Null mice is associated with decreased deposition of extracellular matrix and reduced tumor cell apoptosis", Molecular Cancer Research, 2:215-224
Precautions
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Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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