Full Product Name
IL-9R (Phospho-Ser519) Antibody
Product Synonym Names
IL9R; IL9RX; IL9RY; Interleukin-9 receptor precursor
Product Gene Name
anti-IL-9R antibody
[Similar Products]
Product Synonym Gene Name
IL9R[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q01113
Specificity
IL-9R (Phospho-Ser519) Antibody detects endogenous levels of IL-9R only when phosphorylated at Ser519.
Purity/Purification
Purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.
Form/Format
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1 mg/ml (lot specific)
Target Modification
Phospho
Modification Sites
H:S519
Immunogen
The antiserum was produced against synthesized peptide derived from human IL-9R around the phosphorylation site of Ser519.
Preparation and Storage
Stable at -20 degree C for at least 1 year.
Other Notes
Small volumes of anti-IL-9R antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-IL-9R antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA (EIA)
Application Notes for anti-IL-9R antibody
WB: 1:500~1:1000
IHC: 1:50~1:100
IF: 1:100~1:500
ELISA: 1:20000
Immunofluorescence (IF) of anti-IL-9R antibody
Immunofluorescence analysis of HUVEC cells, using IL-9R (Phospho-Ser519) Antibody. The picture on the right is blocked with the phospho peptide.
Immunohistochemistry (IHC) of anti-IL-9R antibody
Immunohistochemistry analysis of paraffin-embedded human lymph node, using IL-9R (Phospho-Ser519) Antibody. The picture on the right is blocked with the phospho peptide.
Western Blot (WB) of anti-IL-9R antibody
Western blot analysis of lysates from HUVEC cells, using IL-9R (Phospho-Ser519) Antibody. The lane on the right is blocked with the phospho peptide.
NCBI/Uniprot data below describe general gene information for IL-9R. It may not necessarily be applicable to this product.
NCBI Accession #
NP_002177.2
[Other Products]
NCBI GenBank Nucleotide #
NM_002186.2
[Other Products]
UniProt Primary Accession #
Q01113
[Other Products]
UniProt Secondary Accession #
Q14634; Q8WWU1; Q96TF0; B9ZVT0[Other Products]
UniProt Related Accession #
Q01113[Other Products]
NCBI Official Full Name
interleukin-9 receptor isoform 1
NCBI Official Synonym Full Names
interleukin 9 receptor
NCBI Official Symbol
IL9R??[Similar Products]
NCBI Official Synonym Symbols
CD129; IL-9R
??[Similar Products]
NCBI Protein Information
interleukin-9 receptor
UniProt Protein Name
Interleukin-9 receptor
UniProt Synonym Protein Names
CD_antigen: CD129
UniProt Gene Name
IL9R??[Similar Products]
UniProt Synonym Gene Names
IL-9 receptor; IL-9R??[Similar Products]
NCBI Summary for IL-9R
The protein encoded by this gene is a cytokine receptor that specifically mediates the
biological effects of interleukin 9 (IL9). The functional IL9 receptor complex requires this protein as well as the interleukin 2 receptor, gamma (IL2RG), a common gamma subunit shared by the receptors of many different cytokines. The ligand binding of this receptor leads to the activation of various JAK kinases and STAT proteins, which connect to different biologic responses. This gene is located at the pseudoautosomal regions of X and Y chromosomes. Genetic studies suggested an association of this gene with the development of asthma. Multiple pseudogenes on chromosome 9, 10, 16, and 18 have been described. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2008]
UniProt Comments for IL-9R
This is a receptor for interleukin-9.
Research Articles on IL-9R
1. Results show that silencing of the IL-9R gene alleviates the drug resistance of diffuse large B-cell lymphoma (DLBCL) cell lines that is induced by IL-9 suggesting that IL-9R is involved in chemotherapy drug resistance of DLBCL.
Precautions
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Disclaimer
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