Product Name
5-methyltetrahydrofolate-homocysteine methyltransferase reductase (MTRR), ELISA Kit
Full Product Name
Rat Methionine synthase reductase, MTRR ELISA Kit
Product Synonym Names
Rat Methionine synthase reductase (MTRR) ELISA kit; MGC129643; MSR; cblE; [methionine synthase]-cobalamin methyltransferase (cob (II) alamin reducing) ; methionine synthase reductase; 5-methyltetrahydrofolate-homocysteine methyltransferase reductase
Product Gene Name
MTRR elisa kit
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Request for Current Manual Insert
Request Current Manual
3D Structure
ModBase 3D Structure for Q498R1
Preparation and Storage
Store all reagents at 2-8 degree C
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
Other Notes
Small volumes of MTRR elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms for MTRR purchase
MBS9333809 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the 5-methyltetrahydrofolate-homocysteine methyltransferase reductase (MTRR) ELISA Kit target analytes in
biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing MTRR. The ELISA analytical biochemical technique of the MBS9333809 kit is based on MTRR antibody-MTRR antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect MTRR antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, MTRR. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
NCBI/Uniprot data below describe general gene information for MTRR. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001034092.1
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NCBI GenBank Nucleotide #
NM_001039003.1
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UniProt Primary Accession #
Q498R1
[Other Products]
UniProt Secondary Accession #
D3ZDG8[Other Products]
UniProt Related Accession #
Q498R1[Other Products]
Molecular Weight
78,025 Da
NCBI Official Full Name
methionine synthase reductase
NCBI Official Synonym Full Names
5-methyltetrahydrofolate-homocysteine methyltransferase reductase
NCBI Official Symbol
Mtrr??[Similar Products]
NCBI Official Synonym Symbols
MSR
??[Similar Products]
NCBI Protein Information
methionine synthase reductase
UniProt Protein Name
Methionine synthase reductase
Protein Family
Methionine synthase reductase
UniProt Gene Name
Mtrr??[Similar Products]
UniProt Synonym Gene Names
MSR??[Similar Products]
UniProt Entry Name
MTRR_RAT
UniProt Comments for MTRR
Function: Involved in the reductive regeneration of cob(I)alamin (vitamin B12) cofactor required for the maintenance of methionine synthase in a functional state. Necessary for utilization of methylgroups from the folate cycle, thereby affecting transgenerational epigenetic inheritance. Folate pathway donates methyl groups necessary for cellular methylation and affects different pathways such as DNA methylation, possibly explaining the transgenerational epigenetic inheritance effects
Catalytic activity: 2 [methionine synthase]-methylcob(I)alamin + 2 S-adenosylhomocysteine + NADP+ = 2 [methionine synthase]-cob(II)alamin + NADPH + 2 S-adenosyl-L-methionine.
Cofactor: FAD
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.