Product Name
FAM20C, Polyclonal Antibody
Full Product Name
FAM20C antibody - C-terminal region
Product Gene Name
anti-FAM20C antibody
[Similar Products]
Product Synonym Gene Name
DMP4; RNS; DMP-4[Similar Products]
Antibody/Peptide Pairs
FAM20C peptide (MBS3234442) is used for blocking the activity of FAM20C antibody (MBS3209483)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence
Synthetic peptide located within the following region: NETFIIHLDN GRGFGKYSHD ELSILVPLQQ CCRIRKSTYL RLQLLAKEEY
3D Structure
ModBase 3D Structure for Q8IXL6
Species Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish
Purity/Purification
Affinity Purified
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Homology
Cow: 93%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 93%; Rat: 100%; Zebrafish: 93%
Immunogen
The immunogen is a synthetic peptide directed towards the C terminal region of human FAM20C
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Other Notes
Small volumes of anti-FAM20C antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-FAM20C antibody
This is a rabbit polyclonal antibody against FAM20C. It was validated on Western Blot using a cell lysate as a positive control.
Target Description: FAM20C belongs to the FAM20 family. FAM20C is a calcium-binding protein which may play a role in dentin mineralization. Mutations in FAM20C are associated with lethal osteosclerotic bone dysplasia (Raine Syndrome), highlighting a crucial molecule in bone development.
Product Categories/Family for anti-FAM20C antibody
Polyclonal; Membrane Protein; Developmental Biology; Disease Related; DNA/RNA/Protein Interactions;
Applications Tested/Suitable for anti-FAM20C antibody
Western Blot (WB)
Western Blot (WB) of anti-FAM20C antibody
WB Suggested Anti-FAM20C Antibody Titration: 0.2-1 ug/ml
Positive Control: NTERA2 cell lysate
NCBI/Uniprot data below describe general gene information for FAM20C. It may not necessarily be applicable to this product.
NCBI Accession #
NP_064608
[Other Products]
NCBI GenBank Nucleotide #
NM_020223
[Other Products]
UniProt Primary Accession #
Q8IXL6
[Other Products]
UniProt Related Accession #
Q8IXL6[Other Products]
NCBI Official Full Name
extracellular serine/threonine protein kinase FAM20C
NCBI Official Synonym Full Names
FAM20C golgi associated secretory pathway kinase
NCBI Official Symbol
FAM20C??[Similar Products]
NCBI Official Synonym Symbols
RNS; DMP4; G-CK; DMP-4; GEF-CK
??[Similar Products]
NCBI Protein Information
extracellular serine/threonine protein kinase FAM20C
UniProt Protein Name
Extracellular serine/threonine protein kinase FAM20C
UniProt Synonym Protein Names
Dentin matrix protein 4; DMP-4; Golgi-enriched fraction casein kinase; GEF-CK; Protein FAM20C
Protein Family
Extracellular serine/threonine protein kinase
UniProt Gene Name
FAM20C??[Similar Products]
UniProt Synonym Gene Names
DMP4; DMP-4; GEF-CK??[Similar Products]
UniProt Entry Name
DMP4_HUMAN
NCBI Summary for FAM20C
This gene encodes a member of the family of secreted protein kinases. The encoded protein binds calcium and phosphorylates proteins involved in bone mineralization. Mutations in this gene are associated with the autosomal recessive disorder Raine syndrome. [provided by RefSeq, Apr 2014]
Research Articles on FAM20C
1. that FAM20C may affect the biomineralization by the means more than local phosphorylation of extracellular matrix proteins and systemic phosphorus homeostasis
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
