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Cytochrome c oxidase subunit 4 isoform 2, mitochondrial (COX4I2), Recombinant P

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產(chǎn)品名稱: Cytochrome c oxidase subunit 4 isoform 2, mitochondrial (COX4I2), Recombinant P
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簡單介紹

Cytochrome c oxidase subunit 4 isoform 2, mitochondrial (COX4I2), Recombinant Protein


Cytochrome c oxidase subunit 4 isoform 2, mitochondrial (COX4I2), Recombinant P  的詳細(xì)介紹
Product Name

Cytochrome c oxidase subunit 4 isoform 2, mitochondrial (COX4I2), Recombinant Protein

Full Product Name

Recombinant Human Cytochrome c oxidase subunit 4 isoform 2, mitochondrial (COX4I2) , partial

Product Gene Name

COX4I2 recombinant protein

[Similar Products]
Product Synonym Gene Name
COX4I2[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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Sequence Positions
21-104. Partial.
Sequence
MHSSEGTTRG GGKMSPYTNC YAQRYYPMPE EPFCTELNAE EQALKEKEKG SWTQLTHAEK VALYRLQFNE TFAEMNRRSN EWKT
OMIM
607976
3D Structure
ModBase 3D Structure for Q96KJ9
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Species
Human
Storage Buffer
Tris-based buffer, 50% glycerol
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of COX4I2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for
COX4I2 recombinant protein
Cytochrome c oxidase (COX), the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may be involved in the regulation and assembly of the complex. This nuclear gene encodes isoform 2 of subunit IV. Isoform 1 of subunit IV is encoded by a different gene, however, the two genes show a similar structural organization. Subunit IV is the largest nuclear encoded subunit which plays a pivotal role in COX regulation.
NCBI/Uniprot data below describe general gene information for COX4I2. It may not necessarily be applicable to this product.
NCBI GI #
17999526
NCBI GeneID
84701
NCBI Accession #
NP_115998.2 [Other Products]
NCBI GenBank Nucleotide #
NM_032609.2 [Other Products]
UniProt Primary Accession #
Q96KJ9 [Other Products]
UniProt Secondary Accession #
Q6GTF4; Q9H0Z4[Other Products]
UniProt Related Accession #
Q96KJ9[Other Products]
Molecular Weight
20,010 Da
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NCBI Official Full Name
cytochrome c oxidase subunit 4 isoform 2, mitochondrial
NCBI Official Synonym Full Names
cytochrome c oxidase subunit 4I2
NCBI Official Symbol
COX4I2??[Similar Products]
NCBI Official Synonym Symbols
COX4; COX4B; COX4-2; COX4L2; COXIV-2; dJ857M17.2
??[Similar Products]
NCBI Protein Information
cytochrome c oxidase subunit 4 isoform 2, mitochondrial
UniProt Protein Name
Cytochrome c oxidase subunit 4 isoform 2, mitochondrial
UniProt Synonym Protein Names
Cytochrome c oxidase subunit IV isoform 2; COX IV-2
UniProt Gene Name
COX4I2??[Similar Products]
UniProt Synonym Gene Names
COX4L2; COX IV-2??[Similar Products]
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NCBI Summary for COX4I2
Cytochrome c oxidase (COX), the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may be involved in the regulation and assembly of the complex. This nuclear gene encodes isoform 2 of subunit IV. Isoform 1 of subunit IV is encoded by a different gene, however, the two genes show a similar structural organization. Subunit IV is the largest nuclear encoded subunit which plays a pivotal role in COX regulation. [provided by RefSeq, Jul 2008]
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UniProt Comments for COX4I2
This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport.
Research Articles on COX4I2
1. Identification of three transcription factors that bind a conserved responsive element of the COX4I2 gene, namely recombination signal sequence-binding protein Jkappa (RBPJ), coiled-coil-helix-coiled-coil-helix domain 2 (CHCHD2) and CXXC finger protein 5 (CXXC5).
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Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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