Product Name
Adenylate kinase 2, mitochondrial (Ak2), Recombinant Protein
Full Product Name
Recombinant Rat Adenylate kinase 2, mitochondrial (Ak2)
Product Gene Name
Ak2 recombinant protein
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
1-239aa, Full length protein
Sequence
MAPNALAPEP EHPEGIRAVL LGPPGAGKGT QAPKLAENFC VCHLATGDML RAMVASGSEL GKKLKATMDA GKLVSDEMVV ELIEKNLETP SCKNGFLLDG FPRTVKQAEM LDDLMDKRKE KLDSVIEFSI QDSLLIRRIT GRLIHPKSGR SYHEEFNPPK EAMKDDITGE PLIRRSDDNE KALKTRLEAY HTQTTPLVEY YRKRGIHCAI DASQTPDVVF ASILAAFSKA TCKDLVMFV
3D Structure
ModBase 3D Structure for P29410
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Storage Buffer
Tris-based buffer, 50% glycerol
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of Ak2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
Ak2 recombinant protein
Adenylate kinases are involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate groups among adenine nucleotides. Three isozymes of adenylate kinase, namely 1, 2, and 3, have been identified in vertebrates; this gene encodes isozyme 2. Expression of these isozymes is tissue-specific and developmentally regulated. Isozyme 2 is localized in the mitochondrial intermembrane space and may play a role in apoptosis. Two transcript variants encoding distinct isoforms have been identified for this gene.
NCBI/Uniprot data below describe general gene information for Ak2. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001029139.1
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NCBI GenBank Nucleotide #
NM_001033967.2
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UniProt Primary Accession #
P29410
[Other Products]
UniProt Secondary Accession #
Q6P7C6[Other Products]
UniProt Related Accession #
P29410[Other Products]
Molecular Weight
25,530 Da
NCBI Official Full Name
adenylate kinase 2, mitochondrial isoform b
NCBI Official Synonym Full Names
adenylate kinase 2
NCBI Official Symbol
Ak2??[Similar Products]
NCBI Protein Information
adenylate kinase 2, mitochondrial
UniProt Protein Name
Adenylate kinase 2, mitochondrial
UniProt Synonym Protein Names
ATP-AMP transphosphorylase 2
UniProt Gene Name
Ak2??[Similar Products]
UniProt Synonym Gene Names
AK 2??[Similar Products]
UniProt Comments for Ak2
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. Plays a key role in hematopoiesis.
Research Articles on Ak2
1. AK2 participates in the pathophysiological process of temporal lobe epilepsy.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
