For Research Use Only. Not for use in diagnostic procedures.

Store at 4 degree C.

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Small volumes of COL6a1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS9139110 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Collagen Type VI Alpha 1 (COL6a1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing COL6a1. The ELISA analytical biochemical technique of the MBS9139110 kit is based on COL6a1 antibody-COL6a1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect COL6a1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, COL6a1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Product Overview: The ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of samples in cell culture supernatant, serum, plasma (EDTA, citrate, heparin).
Intended Use: This Rat Collagen Type VI Alpha 1 (COL6a1) ELISA kit is intended for laboratory research use only and not for use in diagnostic or therapeutic procedures. The stop solution changes color from blue to yellow and the intensity of the color is measured at 450 nm using a spectrophotometer. In order to measure the concentration of Rat Collagen Type VI Alpha 1 (COL6a1) in the sample, this Rat Collagen Type VI Alpha 1 (COL6a1) ELISA Kit includes a set of calibration standards. The calibration standards are assayed at the same time as the samples and allow the operator to produce a standard curve of optical density versus Rat Collagen Type VI Alpha 1 (COL6a1) concentration. The concentration of the samples is then determined by comparing the O.D. of the samples to the standard curve.

108,529 Da

collagen type VI alpha 1 chain

collagen alpha-1(VI) chain

Collagen alpha-1(VI) chain

The collagens are a superfamily of proteins that play a role in maintaining the integrity of various tissues. Collagens are extracellular matrix proteins and have a triple-helical domain as their common structural element. Collagen VI is a major structural component of microfibrils. The basic structural unit of collagen VI is a heterotrimer of the alpha1(VI), alpha2(VI), and alpha3(VI) chains. The alpha2(VI) and alpha3(VI) chains are encoded by the COL6A2 and COL6A3 genes, respectively. The protein encoded by this gene is the alpha 1 subunit of type VI collagen (alpha1(VI) chain). Mutations in the genes that code for the collagen VI subunits result in the autosomal dominant disorder, Bethlem myopathy. [provided by RefSeq, Jul 2008]

Collagen VI acts as a cell-binding protein.

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