Product Name
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 (Pfkfb4), Recombinant Protein
Full Product Name
Recombinant Mouse 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 (Pfkfb4)
Product Gene Name
Pfkfb4 recombinant protein
[Similar Products]
Product Synonym Gene Name
Pfkfb4[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
1-469aa, full length protein
Sequence
MASPRELTQN PLKKIWMPYS NGRPALHASQ RGVCMTNCPT LIVMVGLPAR GKTYISKKLT RYLNWIGVPT REFNVGQYRR DIVKTYKSFE FFLPDNEEGL KIRKQCALAA LSDVRKFLSE EGGHVAVFDA TNTTRERRAM IFNFGEQNGY KTFFVESICV DPEVVAANIV QVKLGSPDYV NRDSDEATED FMRRIECYEN SYESLDEDLD RDLSYIKIMD VGQSYVVNRV ADHIQSRIVY YLMNIHVTPR SIYLCRHGES ELNLKGRIGG DPGLSPRGRE FSKHLAQFIS DQNIKDLKVW TSQMKRTIQT AEALSVPYEQ WKVLNEIDAG VCEEMTYEEI QDHYPLEFAL RDQDKYRYRY PKGESYEDLV QRLEPVIMEL ERQENVLVIC HQAVMRCLLA YFLDKAAEEL PYLKCPLHTV LKLTPVAYGC KVESIFLNVA AVNTHRDRPQ NVDISRPSEE ALVTVPAHQ
3D Structure
ModBase 3D Structure for Q6DTY7
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Storage Buffer
Tris-based buffer, 50% glycerol
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of Pfkfb4 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for Pfkfb4. It may not necessarily be applicable to this product.
NCBI Accession #
NP_766607.3
[Other Products]
NCBI GenBank Nucleotide #
NM_173019.5
[Other Products]
UniProt Primary Accession #
Q6DTY7
[Other Products]
UniProt Secondary Accession #
Q5UD55; Q5UD56; Q5UD57; Q5Y296; Q6PFE8[Other Products]
UniProt Related Accession #
Q6DTY7[Other Products]
Molecular Weight
50,246 Da
NCBI Official Full Name
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4
NCBI Official Synonym Full Names
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
NCBI Official Symbol
Pfkfb4??[Similar Products]
NCBI Official Synonym Symbols
C230090D14
??[Similar Products]
NCBI Protein Information
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4
UniProt Protein Name
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4
UniProt Synonym Protein Names
6PF-2-K/Fru-2,6-P2ase testis-type isozymeIncluding the following 2 domains:6-phosphofructo-2-kinase (EC:2.7.1.105)Fructose-2,6-bisphosphatase (EC:3.1.3.46)
Protein Family
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase
UniProt Gene Name
Pfkfb4??[Similar Products]
UniProt Synonym Gene Names
6PF-2-K/Fru-2,6-P2ase 4; PFK/FBPase 4??[Similar Products]
UniProt Comments for Pfkfb4
Synthesis and degradation of fructose 2,6-bisphosphate.
Research Articles on Pfkfb4
1. Inhibition of PFKFB4 suppresses glycolysis and proliferation of multiple human cancer cell lines.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
