Product Name
A disintegrin and metalloproteinase with thrombospondin motifs 15 (Adamts15), Recombinant Protein
Full Product Name
Recombinant Mouse A disintegrin and metalloproteinase with thrombospondin motifs 15 (Adamts15)
Product Gene Name
Adamts15 recombinant protein
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Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
213-950aa, Full Length of Mature Protein
Sequence
FVSIPRYVET LVVADESMVK FHGADLEHYL LTLLATAARL YRHPSILNPI NIVVVKVLLL GDRDTGPKVT GNAALTLRNF CAWQKKLNKV SDKHPEYWDT AILFTRQDLC GATTCDTLGM ADVGTMCDPK RSCSVIEDDG LPSAFTTAHE LGHVFNMPHD NVKVCEEVFG KLRANHMMSP TLIQIDRANP WSACSAAIIT DFLDSGHGDC LLDQPSKPIT LPEDLPGTSY SLSQQCELAF GVGSKPCPYM QYCTKLWCTG KAKGQMVCQT RHFPWADGTS CGEGKFCLKG ACVERHNPNK YRVDGSWAKW EPYGSCSRTC GGGVQLARRQ CSNPTPANGG KYCEGVRVKY RSCNLEPCPS SASGKSFREE QCEAFNGYNH STNRLTLAVA WVPKYSGVSP RDKCKLICRA NGTGYFYVLA PKVVDGTLCT PDSTSVCVQG KCIKAGCDGN LGSKKKFDKC GVCGGDNKSC KRVTGLFTKP MHGYNFVVAI PAGASSIDIR QRGYKGLIGD DNYLALKNSQ GKYLLNGHFV VSAVERDLVV KGSVLRYSGT GTAVESLQAS RPILEPLTVE VLSVGKMTPP RVRYSFYLPK EPREDKSTRP KDPRGSPVLR NSVLSLSNQV EQPDNRPPAR WVAGSWGPCS VSCGSGLQKR AVDCRDSPGQ QGASACDVDH RPLEKRACGE PCPTWELGNW SPCSKSCGRG FKRRPLKCVG HGGRLLARDQ CDLRRKPQEL DFCVLRPC
3D Structure
ModBase 3D Structure for P59384
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Storage Buffer
Tris-based buffer, 50% glycerol
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of Adamts15 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
Adamts15 recombinant protein
This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. ADAMTS family members share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. This protein has a high sequence similarity to the proteins encoded by ADAMTS1 and ADAMTS8.
NCBI/Uniprot data below describe general gene information for Adamts15. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001019310.1
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NCBI GenBank Nucleotide #
NM_001024139.1
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UniProt Primary Accession #
P59384
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UniProt Secondary Accession #
Q504Z2; Q91Z56[Other Products]
UniProt Related Accession #
P59384[Other Products]
Molecular Weight
103,938 Da
NCBI Official Full Name
A disintegrin and metalloproteinase with thrombospondin motifs 15 isoform 1 preproprotein
NCBI Official Synonym Full Names
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 15
NCBI Official Symbol
Adamts15??[Similar Products]
NCBI Protein Information
A disintegrin and metalloproteinase with thrombospondin motifs 15
UniProt Protein Name
A disintegrin and metalloproteinase with thrombospondin motifs 15
Protein Family
A disintegrin and metalloproteinase with thrombospondin motifs
UniProt Gene Name
Adamts15??[Similar Products]
UniProt Synonym Gene Names
ADAM-TS 15; ADAM-TS15; ADAMTS-15??[Similar Products]
NCBI Summary for Adamts15
This gene encodes a member of "a disintegrin and metalloproteinase with thrombospondin motifs" (ADAMTS) family of multi-domain matrix-associated metalloendopeptidases that have diverse roles in tissue morphogenesis and pathophysiological remodeling, in inflammation and in vascular
biology. The encoded preproprotein undergoes proteolytic processing to generate an active versicanase enzyme. This gene is located adjacent to a related ADAMTS gene (Adamts8) on chromosome 9. [provided by RefSeq, Jul 2016]
Research Articles on Adamts15
1. spiking parvalbumin interneurons enwrapped in the perineuronal net express the metallopeptidases Adamts15 in mice.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
