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Gamma-aminobutyric acid receptor subunit gamma-2 (GABRG2), Recombinant Protein

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產(chǎn)品名稱: Gamma-aminobutyric acid receptor subunit gamma-2 (GABRG2), Recombinant Protein
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Gamma-aminobutyric acid receptor subunit gamma-2 (GABRG2), Recombinant Protein


Gamma-aminobutyric acid receptor subunit gamma-2 (GABRG2), Recombinant Protein  的詳細(xì)介紹
Product Name

Gamma-aminobutyric acid receptor subunit gamma-2 (GABRG2), Recombinant Protein

Full Product Name

Recombinant Human Gamma-aminobutyric acid receptor subunit gamma-2 (GABRG2), partial

Product Gene Name

GABRG2 recombinant protein

[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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Sequence Positions
40-273
Sequence
QKSDDDYEDY ASNKTWVLTP KVPEGDVTVI LNNLLEGYDN KLRPDIGVKP TLIHTDMYVN SIGPVNAINM EYTIDIFFAQ TWYDRRLKFN STIKVLRLNS NMVGKIWIPD TFFRNSKKAD AHWITTPNRM LRIWNDGRVL YTLRLTIDAE CQLQLHNFPM DEHSCPLEFS SYGYPREEIV YQWKRSSVEV GDTRSWRLYQ FSFVGLRNTT EVVKTTSGDY VVMSVYFDLS RRMG
OMIM
137164
3D Structure
ModBase 3D Structure for P18507
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Species
Homo sapiens (Human)
Storage Buffer
Tris-based buffer, 50% glycerol
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of GABRG2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for GABRG2. It may not necessarily be applicable to this product.
NCBI GI #
38788135
NCBI GeneID
2566
NCBI Accession #
NP_000807.2 [Other Products]
NCBI GenBank Nucleotide #
NM_000816.3 [Other Products]
UniProt Primary Accession #
P18507 [Other Products]
UniProt Secondary Accession #
Q6GRL6; Q6PCC3; Q9UDB3; Q9UN15; F5HB82[Other Products]
UniProt Related Accession #
P18507[Other Products]
Molecular Weight
59,344 Da
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NCBI Official Full Name
gamma-aminobutyric acid receptor subunit gamma-2 isoform 2
NCBI Official Synonym Full Names
gamma-aminobutyric acid type A receptor gamma2 subunit
NCBI Official Symbol
GABRG2??[Similar Products]
NCBI Official Synonym Symbols
CAE2; ECA2; GEFSP3
??[Similar Products]
NCBI Protein Information
gamma-aminobutyric acid receptor subunit gamma-2
UniProt Protein Name
Gamma-aminobutyric acid receptor subunit gamma-2
UniProt Synonym Protein Names
GABA(A) receptor subunit gamma-2
Protein Family
Gamma-aminobutyric acid receptor
UniProt Gene Name
GABRG2??[Similar Products]
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NCBI Summary for GABRG2
This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammlian brain, where it acts at GABA-A receptors, which are ligand-gated chloride channels. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. Mutations in this gene have been associated with epilepsy and febrile seizures. Multiple transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
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UniProt Comments for GABRG2
Component of the heteropentameric receptor for GABA, the major inhibitory neurotransmitter in the vertebrate brain. Functions also as histamine receptor and mediates cellular responses to histamine. Functions as receptor for diazepines and various anesthetics, such as pentobarbital; these are bound at a separate allosteric effector . Functions as ligand-gated chloride channel.
Research Articles on GABRG2
1. The aim of this case-control study is to investigate whether GABRG2 polymorphisms contribute to susceptibility for Febrile seizure and epilepsy in pooled data of three cohorts, from Malaysia (composed of Malay, Chinese, and Indian), Hong Kong, and Korea.
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Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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