2-oxoglutarate dehydrogenase, mitochondrial; 2-oxoglutarate dehydrogenase complex component E1; OGDC-E1; Alpha-ketoglutarate dehydrogenase; Ogdh; Kiaa4192; 1.2.4.2

For Research Use Only. Not for use in diagnostic procedures.

Store at 4 degree C

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Small volumes of Ogdh elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS9427916 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the 2-oxoglutarate dehydrogenase (Ogdh) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing Ogdh. The ELISA analytical biochemical technique of the MBS9427916 kit is based on Ogdh antibody-Ogdh antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect Ogdh antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, Ogdh. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

117,758 Da

oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)

2-oxoglutarate dehydrogenase, mitochondrial

2-oxoglutarate dehydrogenase, mitochondrial

Kiaa4192; OGDC-E1??[Similar Products]

OGDH: The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components: 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3). Belongs to the alpha-ketoglutarate dehydrogenase family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Amino Acid Metabolism - lysine degradation; Amino Acid Metabolism - tryptophan; Carbohydrate Metabolism - citrate (TCA) cycle; EC 1.2.4.2; Mitochondrial; Oxidoreductase

Chromosomal Location of Human Ortholog: 11|11 A1

Cellular Component: mitochondrion; oxoglutarate dehydrogenase complex

Molecular Function: chaperone binding; heat shock protein binding; oxoglutarate dehydrogenase (succinyl-transferring) activity

Biological Process: 2-oxoglutarate metabolic process; cerebellar cortex development; hippocampus development; NADH metabolic process; pyramidal neuron development; striatum development; succinyl-CoA metabolic process; tangential migration from the subventricular zone to the olfactory bulb; thalamus development; tricarboxylic acid cycle

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