Human Actin-binding Rho-activating protein (ABRA) ELISA kit; STARS; striated muscle activator of Rho-dependent signaling; actin-binding Rho activating protein

For Research Use Only. Not for use in diagnostic procedures.

Store all reagents at 2-8 degree C

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Small volumes of ABRA elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS9327015 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the actin-binding Rho activating protein (ABRA) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing ABRA. The ELISA analytical biochemical technique of the MBS9327015 kit is based on ABRA antibody-ABRA antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect ABRA antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, ABRA. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

43,117 Da

actin-binding Rho activating protein

actin-binding Rho-activating protein; striated muscle activator of Rho-dependent signaling

Actin-binding Rho-activating protein

STARS??[Similar Products]

ABRA_HUMAN

ABRA: Acts as an activator of serum response factor (SRF)- dependent transcription possibly by inducing nuclear translocation of MKL1 or MKL2 and through a mechanism requiring Rho-actin signaling.

Protein type: Actin-binding; Contractile; Transcription, coactivator/corepressor

Chromosomal Location of Human Ortholog: 8q23.1

Cellular Component: sarcomere; plasma membrane; actin cytoskeleton

Molecular Function: transcription coactivator activity; actin binding

Biological Process: transcription, DNA-dependent; protein import into nucleus, translocation; positive regulation of Rho protein signal transduction; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription factor activity

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