Product Name
3-hydroxyacyl-CoA dehydratase 1 (PTPLA), Recombinant Protein
Full Product Name
Recombinant Dog 3-hydroxyacyl-CoA dehydratase 1 (PTPLA), partial
Product Gene Name
PTPLA recombinant protein
[Similar Products]
Product Synonym Gene Name
PTPLA[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q4W1W1
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Species
Canis familiaris (Dog) (Canis lupus familiaris)
Storage Buffer
Tris-based buffer, 50% glycerol
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of PTPLA recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for PTPLA. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001020440.1
[Other Products]
NCBI GenBank Nucleotide #
NM_001025269.1
[Other Products]
UniProt Primary Accession #
Q4W1W1
[Other Products]
UniProt Secondary Accession #
Q4W1W0[Other Products]
UniProt Related Accession #
Q4W1W1[Other Products]
Molecular Weight
28,857 Da
NCBI Official Full Name
very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 1
NCBI Official Synonym Full Names
3-hydroxyacyl-CoA dehydratase 1
NCBI Official Symbol
HACD1??[Similar Products]
NCBI Official Synonym Symbols
PTPLA
??[Similar Products]
NCBI Protein Information
very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 1
UniProt Protein Name
Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 1
UniProt Synonym Protein Names
3-hydroxyacyl-CoA dehydratase 1Curated; HACD1Curated; Protein-tyrosine phosphatase-like member ACurated
UniProt Gene Name
HACD1??[Similar Products]
UniProt Synonym Gene Names
PTPLACurated; HACD1Curated??[Similar Products]
UniProt Comments for PTPLA
Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates in the production of VLCFAs of different chain lengths that are involved in multiple
biological processes as precursors of membrane lipids and lipid mediators.
Research Articles on PTPLA
1. Longitudinal analyses in myopathic Labrador retrievers reveal several membrane-associated defects, including ultrastructural triads dysmorphogenesis and mitochondrial mislocalization.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
