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pleckstrin homology domain containing, family M (with RUN domain) member 1, ELI

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產(chǎn)品名稱: pleckstrin homology domain containing, family M (with RUN domain) member 1, ELI
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pleckstrin homology domain containing, family M (with RUN domain) member 1, ELISA Kit


pleckstrin homology domain containing, family M (with RUN domain) member 1, ELI  的詳細(xì)介紹
Product Name

pleckstrin homology domain containing, family M (with RUN domain) member 1 (PLEKHM1), ELISA Kit

Full Product Name

Mouse Pleckstrin homology domain-containing family M member 1, PLEKHM1 ELISA Kit

Product Synonym Names
Mouse Pleckstrin homology domain-containing family M member 1 (PLEKHM1) ELISA kit; AP162; B2; KIAA0356; OPTB6; 162 kDa adapter protein; pleckstrin homology domain containing; family M (with RUN domain) member 1
Product Gene Name

PLEKHM1 elisa kit

[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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Request for Current Manual Insert
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3D Structure
ModBase 3D Structure for Q7TSI1
Species Reactivity
Mouse
Preparation and Storage
Store all reagents at 2-8 degree C
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
Other Notes
Small volumes of PLEKHM1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms for PLEKHM1 purchase
MBS9331744 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the pleckstrin homology domain containing, family M (with RUN domain) member 1 (PLEKHM1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing PLEKHM1. The ELISA analytical biochemical technique of the MBS9331744 kit is based on PLEKHM1 antibody-PLEKHM1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect PLEKHM1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, PLEKHM1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for PLEKHM1. It may not necessarily be applicable to this product.
NCBI GI #
33942120
NCBI GeneID
353047
NCBI Accession #
NP_898855.1 [Other Products]
NCBI GenBank Nucleotide #
NM_183034.1 [Other Products]
UniProt Primary Accession #
Q7TSI1 [Other Products]
UniProt Secondary Accession #
Q3U3L2; Q8CHU5[Other Products]
UniProt Related Accession #
Q7TSI1[Other Products]
Molecular Weight
118,535 Da
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NCBI Official Full Name
pleckstrin homology domain-containing family M member 1
NCBI Official Synonym Full Names
pleckstrin homology domain containing, family M (with RUN domain) member 1
NCBI Official Symbol
Plekhm1??[Similar Products]
NCBI Official Synonym Symbols
B2; AP162; BC038943; D330036J23Rik
??[Similar Products]
NCBI Protein Information
pleckstrin homology domain-containing family M member 1; PH domain-containing family M member 1
UniProt Protein Name
Pleckstrin homology domain-containing family M member 1
Protein Family
Pleckstrin homology domain-containing family
UniProt Gene Name
Plekhm1??[Similar Products]
UniProt Synonym Gene Names
PH domain-containing family M member 1??[Similar Products]
UniProt Entry Name
PKHM1_MOUSE
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UniProt Comments for PLEKHM1
PLEKHM1: Involved in vesicular transport in the osteoclast. May have a role in sialyl-lex-mediated transduction of apoptotic signals. Defects in PLEKHM1 are the cause of osteopetrosis autosomal recessive type 6 (OPTB6); also known as autosomal recessive osteopetrosis intermediate form. Osteopetrosis is a rare genetic disease characterized by abnormally dense bone, due to defective resorption of immature bone. The disorder occurs in two forms: a severe autosomal recessive form occurring in utero, infancy, or childhood, and a benign autosomal dominant form occurring in adolescence or *****hood. Autosomal recessive osteopetrosis is usually associated with normal or elevated amount of non-functional osteoclasts.

Protein type: Unknown function

Cellular Component: cytoplasm

Molecular Function: protein binding; metal ion binding
Research Articles on PLEKHM1
1. results indicate that LIS1 is a previously unrecognized regulator of osteoclast formation, microtubule organization, and lysosomal secretion by virtue of its ability to modulate dynein function and Plekhm1
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Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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