Full Product Name
ZFY26 Polyclonal Antibody
Product Synonym Names
Zinc finger FYVE domain-containing protein 26; FYVE domain-containing centrosomal protein; FYVE-CENT; Spastizin; ZFYVE26; KIAA0321
Product Gene Name
anti-ZFY26 antibody
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Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q68DK2
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Immunogen
Synthesized peptide derived from human protein. at AA range: 2381-2430
Preparation and Storage
Store at-20 degree C for 1 year.
Other Notes
Small volumes of anti-ZFY26 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-ZFY26 antibody
Immunohistochemistry (IHC) Paraffin
Application Notes for anti-ZFY26 antibody
IHC-p: 1:50-300
NCBI/Uniprot data below describe general gene information for ZFY26. It may not necessarily be applicable to this product.
NCBI Accession #
NP_056161.2
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NCBI GenBank Nucleotide #
NM_015346.3
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UniProt Primary Accession #
Q68DK2
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UniProt Secondary Accession #
O15035; Q68DT9; Q6AW90; Q6ZR50; Q7Z3A4; Q7Z3I1; Q8N4W7; Q96H43; B1B5Y3; B4E2U3[Other Products]
UniProt Related Accession #
Q68DK2[Other Products]
NCBI Official Full Name
zinc finger FYVE domain-containing protein 26
NCBI Official Synonym Full Names
zinc finger FYVE-type containing 26
NCBI Official Symbol
ZFYVE26??[Similar Products]
NCBI Official Synonym Symbols
SPG15; FYVE-CENT
??[Similar Products]
NCBI Protein Information
zinc finger FYVE domain-containing protein 26
UniProt Protein Name
Zinc finger FYVE domain-containing protein 26
UniProt Synonym Protein Names
FYVE domain-containing centrosomal protein; FYVE-CENT; Spastizin
UniProt Gene Name
ZFYVE26??[Similar Products]
UniProt Synonym Gene Names
KIAA0321; FYVE-CENT??[Similar Products]
NCBI Summary for ZFY26
This gene encodes a protein which contains a FYVE zinc finger binding domain. The presence of this domain is thought to target these proteins to membrane lipids through interaction with phospholipids in the membrane. Mutations in this gene are associated with autosomal recessive spastic paraplegia-15. [provided by RefSeq, Oct 2008]
UniProt Comments for ZFY26
Phosphatidylinositol 3-phosphate-binding protein required for the abcission step in cytokinesis: recruited to the midbody during cytokinesis and acts as a regulator of abcission. May also be required for efficient homologous recombination DNA double-strand break repair.
Research Articles on ZFY26
1. Our protocol showed high specificity and sensitivity for homozygosity detection and facilitated the identification of novel mutations in GAN, GBA2, and ZFYVE26 in four families affected by hereditary spastic paraplegia or Charcot-Marie-Tooth disease
Precautions
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Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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