Product Name
PLEKHM1, Polyclonal Antibody
Full Product Name
PLEKHM1 Antibody - middle region
Product Gene Name
anti-PLEKHM1 antibody
[Similar Products]
Product Synonym Gene Name
B2; AP162; OPTB6;[Similar Products]
Antibody/Peptide Pairs
PLEKHM1 peptide (MBS3245309) is used for blocking the activity of PLEKHM1 antibody (MBS3220508)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence
Synthetic peptide located within the following region: AEDWLDRVRE ALQKVRPQQE DEWVNVQYPD QPEEPPEAPQ GCLSPSDLLS
3D Structure
ModBase 3D Structure for Q69YJ1
Purity/Purification
Affinity purified
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 16% sucrose.
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human PLEKHM1
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Other Notes
Small volumes of anti-PLEKHM1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-PLEKHM1 antibody
The protein encoded by this gene is essential for bone resorption, and may play a critical role in vesicular transport in the osteoclast. Mutations in this gene are associated with autosomal recessive osteopetrosis type 6 (OPTB6). Alternatively spliced transcript variants have been found for this gene.
Product Categories/Family for anti-PLEKHM1 antibody
Polyclonal; Membrane & Traffic; Disease Related;
Applications Tested/Suitable for anti-PLEKHM1 antibody
Western Blot (WB)
Western Blot (WB) of anti-PLEKHM1 antibody
Host: Rabbit
Target Name: PLEKHM1
Sample Tissue: PANC1 Whole Cell lysates
Antibody Dilution: 1ug/ml
NCBI/Uniprot data below describe general gene information for PLEKHM1. It may not necessarily be applicable to this product.
NCBI Accession #
NP_055613.1
[Other Products]
NCBI GenBank Nucleotide #
NM_014798.3
[Other Products]
UniProt Primary Accession #
Q69YJ1
[Other Products]
UniProt Related Accession #
Q9Y4G2[Other Products]
NCBI Official Full Name
pleckstrin homology domain-containing family M member 1 isoform 1
NCBI Official Synonym Full Names
pleckstrin homology and RUN domain containing M1
NCBI Official Symbol
PLEKHM1??[Similar Products]
NCBI Official Synonym Symbols
B2; AP162; OPTA3; OPTB6
??[Similar Products]
NCBI Protein Information
pleckstrin homology domain-containing family M member 1
Protein Family
Pleckstrin homology domain-containing family
NCBI Summary for PLEKHM1
The protein encoded by this gene is essential for bone resorption, and may play a critical role in vesicular transport in the osteoclast. Mutations in this gene are associated with autosomal recessive osteopetrosis type 6 (OPTB6). Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2009]
Research Articles on PLEKHM1
1. identified PLEKHM1 as an endolysosomal adaptor platform that acts as a central hub to integrate endocytic and autophagic pathways at the lysosome
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
