Product Name
ADAM33, Polyclonal Antibody
Full Product Name
ADAM33 antibody - middle region
Product Gene Name
anti-ADAM33 antibody
[Similar Products]
Product Synonym Gene Name
DJ964F7.1; DKFZp434K0521; FLJ35308; FLJ36751; MGC149823; MGC71889; C20orf153[Similar Products]
Antibody/Peptide Pairs
ADAM33 peptide (MBS3234665) is used for blocking the activity of ADAM33 antibody (MBS3209709)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence
Synthetic peptide located within the following region: HDSAQLLTGR AFQGATVGLA PVEGMCRAES SGGVSTDHSE LPIGAAATMA
3D Structure
ModBase 3D Structure for Q9BZ11
Species Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat
Purity/Purification
Affinity Purified
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Homology
Cow: 92%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 93%; Rat: 100%
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human ADAM33
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Other Notes
Small volumes of anti-ADAM33 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-ADAM33 antibody
This is a rabbit polyclonal antibody against ADAM33. It was validated on Western Blot using a cell lysate as a positive control.
Target Description: ADAM33 is a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of
biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. ADAM33 is a type I transmembrane protein implicated in asthma and bronchial hyperresponsiveness.This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This protein is a type I transmembrane protein implicated in asthma and bronchial hyperresponsiveness. Alternative splicing of this gene results in two transcript variants encoding different isoforms.
Product Categories/Family for anti-ADAM33 antibody
Polyclonal; Signal Proteins; Lymphocyte Signaling; Membrane Protein; Developmental Biology; Membrane & Traffic;
Applications Tested/Suitable for anti-ADAM33 antibody
Western Blot (WB)
Western Blot (WB) of anti-ADAM33 antibody
WB Suggested Anti-ADAM33 Antibody Titration: 0.2-1 ug/ml
Positive Control: Hela cell lysate

NCBI/Uniprot data below describe general gene information for ADAM33. It may not necessarily be applicable to this product.
NCBI Accession #
NP_079496
[Other Products]
NCBI GenBank Nucleotide #
NM_025220
[Other Products]
UniProt Primary Accession #
Q9BZ11
[Other Products]
UniProt Related Accession #
Q9BZ11[Other Products]
NCBI Official Full Name
disintegrin and metalloproteinase domain-containing protein 33 isoform alpha preproprotein
NCBI Official Synonym Full Names
ADAM metallopeptidase domain 33
NCBI Official Symbol
ADAM33??[Similar Products]
NCBI Official Synonym Symbols
C20orf153; DJ964F7.1
??[Similar Products]
NCBI Protein Information
disintegrin and metalloproteinase domain-containing protein 33
UniProt Protein Name
Disintegrin and metalloproteinase domain-containing protein 33
Protein Family
Disintegrin and metalloproteinase domain-containing protein
UniProt Gene Name
ADAM33??[Similar Products]
UniProt Synonym Gene Names
C20orf153??[Similar Products]
UniProt Entry Name
ADA33_HUMAN
NCBI Summary for ADAM33
This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This protein is a type I transmembrane protein implicated in asthma and bronchial hyperresponsiveness. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2013]
Research Articles on ADAM33
1. IFN-gamma may participate in airway remodeling in asthma by downregulating the expression of the ADAM33 gene.
Precautions
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Disclaimer
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