Product Name
Nectin 1 (NECTIN1), Polyclonal Antibody
Full Product Name
Nectin 1 Polyclonal Antibody
Product Gene Name
anti-NECTIN1 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q15223
Other Notes
Small volumes of anti-NECTIN1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for NECTIN1. It may not necessarily be applicable to this product.
NCBI Accession #
NP_002846.3
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NCBI GenBank Nucleotide #
NM_002855.4
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UniProt Primary Accession #
Q15223
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UniProt Secondary Accession #
O75465; Q2M3D3; Q9HBE6; Q9HBW2[Other Products]
UniProt Related Accession #
Q15223[Other Products]
Molecular Weight
39,150 Da[Similar Products]
NCBI Official Full Name
nectin-1 isoform 1
NCBI Official Synonym Full Names
nectin cell adhesion molecule 1
NCBI Official Symbol
NECTIN1??[Similar Products]
NCBI Official Synonym Symbols
ED4; PRR; HIgR; HV1S; HVEC; OFC7; PRR1; PVRR; CD111; PVRL1; PVRR1; SK-12; CLPED1; nectin-1
??[Similar Products]
NCBI Protein Information
nectin-1
UniProt Protein Name
Nectin-1
UniProt Synonym Protein Names
Herpes virus entry mediator C; Herpesvirus entry mediator C; HveC; Herpesvirus Ig-like receptor; HIgR; Nectin cell adhesion molecule 1
UniProt Gene Name
NECTIN1??[Similar Products]
UniProt Synonym Gene Names
Herpesvirus entry mediator C; HveC; HIgR??[Similar Products]
NCBI Summary for NECTIN1
This gene encodes an adhesion protein that plays a role in the organization of adherens junctions and tight junctions in epithelial and endothelial cells. The protein is a calcium(2+)-independent cell-cell adhesion molecule that belongs to the immunoglobulin superfamily and has 3 extracellular immunoglobulin-like loops, a single transmembrane domain (in some isoforms), and a cytoplasmic region. This protein acts as a receptor for glycoprotein D (gD) of herpes simplex viruses 1 and 2 (HSV-1, HSV-2), and pseudorabies virus (PRV) and mediates viral entry into epithelial and neuronal cells. Mutations in this gene cause cleft lip and palate/ectodermal dysplasia 1 syndrome (CLPED1) as well as non-syndromic cleft lip with or without cleft palate (CL/P). Alternative splicing results in multiple transcript variants encoding proteins with distinct C-termini. [provided by RefSeq, Oct 2009]
UniProt Comments for NECTIN1
Promotes cell-cell contacts by forming homophilic or heterophilic trans-dimers. Heterophilic interactions have been detected between NECTIN1 and NECTIN3 and between NECTIN1 and NECTIN4. Has some neurite outgrowth-promoting activity.
Research Articles on NECTIN1
1. Pseudorabies virus infects host cells via both human and swine nectin-1.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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