Product Name
Parathyroid hormone/parathyroid hormone-related peptide receptor (PTHR), Polyclonal Antibody
Full Product Name
Parathyroid hormone/parathyroid hormone-related peptide receptor Polyclonal Antibody
Product Synonym Names
Parathyroid hormone/parathyroid hormone-related peptide receptor; PTH1R; PTHR1
Product Gene Name
anti-PTHR antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q03431
Purity/Purification
Affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Immunogen
Synthetic peptide from human protein at AA range: 1268-1341
Storage Buffer
PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.
Preparation and Storage
Store at-20 degree C for 1 year.
Other Notes
Small volumes of anti-PTHR antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-PTHR antibody
Western Blot (WB), Immunohistochemistry (IHC) Paraffin, ELISA (EIA)
Application Notes for anti-PTHR antibody
WB: 1:500-2000
IHC-p: 1:500-200
ELISA: 1:10000-20000
NCBI/Uniprot data below describe general gene information for PTHR. It may not necessarily be applicable to this product.
NCBI Accession #
NP_000307.1
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NCBI GenBank Nucleotide #
NM_000316.2
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UniProt Primary Accession #
Q03431
[Other Products]
UniProt Secondary Accession #
Q2M1U3[Other Products]
UniProt Related Accession #
Q03431[Other Products]
NCBI Official Full Name
parathyroid hormone/parathyroid hormone-related peptide receptor
NCBI Official Synonym Full Names
parathyroid hormone 1 receptor
NCBI Official Symbol
PTH1R??[Similar Products]
NCBI Official Synonym Symbols
PFE; PTHR; PTHR1
??[Similar Products]
NCBI Protein Information
parathyroid hormone/parathyroid hormone-related peptide receptor
UniProt Protein Name
Parathyroid hormone/parathyroid hormone-related peptide receptor
UniProt Synonym Protein Names
PTH/PTHrP type I receptor; PTH/PTHr receptor; Parathyroid hormone 1 receptor; PTH1 receptor
Protein Family
Parathyroid hormone/parathyroid hormone-related peptide receptor
UniProt Gene Name
PTH1R??[Similar Products]
UniProt Synonym Gene Names
PTHR; PTHR1; PTH/PTHr receptor; PTH1 receptor??[Similar Products]
NCBI Summary for PTHR
The protein encoded by this gene is a member of the G-protein coupled receptor family 2. This protein is a receptor for parathyroid hormone (PTH) and for parathyroid hormone-like hormone (PTHLH). The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system. Defects in this receptor are known to be the cause of Jansen's metaphyseal chondrodysplasia (JMC), chondrodysplasia Blomstrand type (BOCD), as well as enchodromatosis. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, May 2010]
UniProt Comments for PTHR
Receptor for parathyroid hormone and for parathyroid hormone-related peptide. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system.
Research Articles on PTHR
1. It seems likely that Mut-PTH1R may be, at least in part, co-localized with Wt-PTH1R by forming a heterodimer, leading to affect the function to each other in Jansen type metaphyseal chondrodysplasia.
Precautions
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Disclaimer
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