Product Name
GPR119, cDNA Clone
Full Product Name
GPR119 cDNA Clone
Product Gene Name
GPR119 cdna clone
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
atggaatcat ctttctcatt tggagtgatc cttgctgtcc tggcctccct catcattgct actaacacac tagtggctgt ggctgtgctg ctgttgatcc acaagaatga tggtgtcagt ctctgcttca ccttgaatct ggctgtggct gacaccttga ttggtgtggc catctctggc ctactcacag accagctctc cagcccttct cggcccacac agaagaccct gtgcagcctg cggatggcat ttgtcacttc ctccgcagct gcctctgtcc tcacggtcat gctgatcacc tttgacaggt accttgccat caagcagccc ttccgctact tgaagatcat gagtgggttc gtggccgggg cctgcattgc cgggctgtgg ttagtgtctt acctcattgg cttcctccca ctcggaatcc ccatgttcca gcagactgcc tacaaagggc agtgcagctt ctttgctgta tttcaccctc acttcgtgct gaccctctcc tgcgttggct tcttcccagc catgctcctc tttgtcttct tctactgcga catgctcaag attgcctcca tgcacagcca gcagattcga aagatggaac atgcaggagc catggctgga ggttatcgat ccccacggac tcccagcgac ttcaaagctc tccgtactgt gtctgttctc attgggagct ttgctctatc ctggaccccc ttccttatca ctggcattgt gcaggtggcc tgccaggagt gtcacctcta cctagtgctg gaacggtacc tgtggctgct cggcgtgggc aactccctgc tcaacccact catctatgcc tattggcaga aggaggtgcg actgcagctc taccacatgg ccctaggagt gaagaaggtg ctcacctcat tcctcctctt tctctcggcc aggaattgtg gcccagagag gcccagggaa agttcctgtc acatcgtcac tatctccagc tcagagtttg atggctaa
Clone Sequence Report
Provided with product shipment
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of GPR119 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for GPR119. It may not necessarily be applicable to this product.
NCBI Accession #
BC126179
[Other Products]
UniProt Secondary Accession #
Q495H7; Q4VBN3[Other Products]
UniProt Related Accession #
Q8TDV5[Other Products]
Molecular Weight
36,889 Da
NCBI Official Full Name
Homo sapiens G protein-coupled receptor 119, mRNA
NCBI Official Synonym Full Names
G protein-coupled receptor 119
NCBI Official Symbol
GPR119??[Similar Products]
NCBI Official Synonym Symbols
GPCR2
??[Similar Products]
NCBI Protein Information
glucose-dependent insulinotropic receptor
UniProt Protein Name
Glucose-dependent insulinotropic receptor
UniProt Synonym Protein Names
G-protein coupled receptor 119
Protein Family
Glucose-dependent insulinotropic receptor
UniProt Gene Name
GPR119??[Similar Products]
UniProt Entry Name
GP119_HUMAN
NCBI Summary for GPR119
This gene encodes a member of the rhodopsin subfamily of G-protein-coupled receptors that is expressed in the pancreas and gastrointestinal tract. The encoded protein is activated by lipid amides including lysophosphatidylcholine and oleoylethanolamide and may be involved in glucose homeostasis. This protein is a potential drug target in the treatment of type 2 diabetes.[provided by RefSeq, Jan 2010]
UniProt Comments for GPR119
GPR119: Receptor for the endogenous fatty-acid ethanolamide oleoylethanolamide (OEA) and lysophosphatidylcholine (LPC). Functions as a glucose-dependent insulinotropic receptor. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Seems to act through a G(s) mediated pathway. Belongs to the G-protein coupled receptor 1 family.
Protein type: GPCR, family 1; Membrane protein, multi-pass; Receptor, GPCR; Membrane protein, integral
Chromosomal Location of Human Ortholog: Xq26.1
Cellular Component: receptor complex
Research Articles on GPR119
1. Describe novel small-molecule GPR119 agonists with high receptor selectivity and capacity to induce glucose-stimulated insulin secretion.
Precautions
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Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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