Product Name
CDP-diacylglycerol--inositol 3-phosphatidyltransferase (Cdipt), Recombinant Protein
Full Product Name
Recombinant Rat CDP-diacylglycerol--inositol 3-phosphatidyltransferase (Cdipt)
Product Synonym Names
Recombinant CDP-diacylglycerol--inositol 3-phosphatidyltransferase (Cdipt); CDP-diacylglycerol--inositol 3-phosphatidyltransferase EC= 2.7.8.11; Phosphatidylinositol synthase; PI synthase; PtdIns synthase
Product Gene Name
Cdipt recombinant protein
[Similar Products]
Product Synonym Gene Name
Cdipt; Pis1[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
MPEENIFLFV PNLIGYARIV FAIISFYFMP CCPFTASSFY LLSGLLDAFD GHAARALNQG TRFGAMLDML TDRCATMCLL VNLALLYPRA TLLFQLSMSL DVASHWLHLH SSVVRGSESH KMIDLSGNPV LRIYYTSRPA LFTLCAGNEL FYCLLYLFNF SEGPLVGSVG LFRMGLWITA PIALLKSIIS VIHLVTAARN MAALDAADRA KKK
Chromosome Location
Chromosome: 1; NC_005100.3 (205389729..205393866). Location: 1q36
3D Structure
ModBase 3D Structure for P70500
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>=90% (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Species
Rattus norvegicus (Rat)
Preparation and Storage
Store at -20 degree C. For extended storage, store at -20 or -80 degree C.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of Cdipt recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for Cdipt. It may not necessarily be applicable to this product.
NCBI Accession #
NP_620254.1
[Other Products]
NCBI GenBank Nucleotide #
NM_138899.2
[Other Products]
UniProt Primary Accession #
P70500
[Other Products]
UniProt Related Accession #
P70500[Other Products]
Molecular Weight
23,613 Da[Similar Products]
NCBI Official Full Name
CDP-diacylglycerol--inositol 3-phosphatidyltransferase
NCBI Official Synonym Full Names
CDP-diacylglycerol--inositol 3-phosphatidyltransferase
NCBI Official Symbol
Cdipt??[Similar Products]
NCBI Official Synonym Symbols
Pis; Pis1
??[Similar Products]
NCBI Protein Information
CDP-diacylglycerol--inositol 3-phosphatidyltransferase; PI synthase; ptdIns synthase; phosphatidylinositol synthase; CDP-diacylglycerol-inositol 3-phosphatidyltransferase
UniProt Protein Name
CDP-diacylglycerol--inositol 3-phosphatidyltransferase
UniProt Synonym Protein Names
Phosphatidylinositol synthase
UniProt Gene Name
Cdipt??[Similar Products]
UniProt Synonym Gene Names
Pis1; PI synthase??[Similar Products]
UniProt Entry Name
CDIPT_RAT
NCBI Summary for Cdipt
catalyzes the formation of phosphatidylinositol and CMP from CDP-diacylglycerol and myo-inositol [RGD, Feb 2006]
UniProt Comments for Cdipt
CDIPT: Catalyzes the biosynthesis of phosphatidylinositol (PtdIns) as well as PtdIns:inositol exchange reaction. May thus act to reduce an excessive cellular PtdIns content. The exchange activity is due to the reverse reaction of PtdIns synthase and is dependent on CMP, which is tightly bound to the enzyme. Belongs to the CDP-alcohol phosphatidyltransferase class-I family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, multi-pass; Transferase; Carbohydrate Metabolism - inositol phosphate; Membrane protein, integral; Lipid Metabolism - glycerophospholipid; EC 2.7.8.11
Cellular Component: Golgi membrane; Golgi apparatus; endoplasmic reticulum membrane; membrane; integral to membrane; plasma membrane
Molecular Function: diacylglycerol binding; manganese ion binding; CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity; alcohol binding; carbohydrate binding
Biological Process: CDP-diacylglycerol metabolic process; phosphatidylinositol biosynthetic process
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
