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GH2, Blocking Peptide

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產(chǎn)品名稱: GH2, Blocking Peptide
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GH2, Blocking Peptide


GH2, Blocking Peptide  的詳細(xì)介紹
Product Name

GH2, Blocking Peptide

Full Product Name

GH2 Antibody (N-term) Blocking Peptide

Product Synonym Names
Growth hormone variant; GH-V; Growth hormone 2; Placenta-specific growth hormone; GH2
Product Gene Name

GH2 blocking peptide

[Similar Products]
Antibody/Peptide Pairs
GH2 peptide (MBS9221730) is used for blocking the activity of GH2 antibody (MBS9203091)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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OMIM
139240
3D Structure
ModBase 3D Structure for P01242
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Cellular Location
Secreted.
Tissue Location
Expressed in the placenta.
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Other Notes
Small volumes of GH2 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for
GH2 blocking peptide
Plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues.
NCBI/Uniprot data below describe general gene information for GH2. It may not necessarily be applicable to this product.
NCBI GI #
20141664
NCBI GeneID
2689
NCBI Accession #
P01242.3 [Other Products]
UniProt Primary Accession #
P01242 [Other Products]
UniProt Secondary Accession #
O14643; O14644; P09587; B1A4H5; B1A4H7[Other Products]
UniProt Related Accession #
P01242[Other Products]
Molecular Weight
27,101 Da
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NCBI Official Full Name
Growth hormone variant
NCBI Official Synonym Full Names
growth hormone 2
NCBI Official Symbol
GH2??[Similar Products]
NCBI Official Synonym Symbols
GHL; GHV; GH-V; GHB2; hGH-V
??[Similar Products]
NCBI Protein Information
growth hormone variant
UniProt Protein Name
Growth hormone variant
UniProt Synonym Protein Names
Growth hormone 2; Placenta-specific growth hormone
Protein Family
Growth hormone
UniProt Gene Name
GH2??[Similar Products]
UniProt Synonym Gene Names
GH-V??[Similar Products]
UniProt Entry Name
SOM2_HUMAN
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NCBI Summary for GH2
The protein encoded by this gene is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. The gene, along with four other related genes, is located at the growth hormone locus on chromosome 17 where they are interspersed in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. The five genes share a remarkably high degree of sequence identity. Alternative splicing generates additional isoforms of each of the five growth hormones, leading to further diversity and potential for specialization. As in the case of its pituitary counterpart, growth hormone 1, the predominant isoform of this particular family member shows similar somatogenic activity, with reduced lactogenic activity. Mutations in this gene lead to placental growth hormone/lactogen deficiency. [provided by RefSeq, Jul 2008]
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UniProt Comments for GH2
GH2: Plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues. Belongs to the somatotropin/prolactin family. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 17q24.2

Cellular Component: extracellular region
Research Articles on GH2
1. genetic association studies in populations in Estonia, Czech Republic, and Bashkortostan/Russia: Data suggest an SNP in GH2 (rs2006123) is associated with ***** height (not body mass index); A-allele is associated with taller stature. [META-ANALYSIS]
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Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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