Product Name
Golgi resident protein GCP60 (Acbd3), Recombinant Protein
Full Product Name
Recombinant Mouse Golgi resident protein GCP60 (Acbd3)
Product Gene Name
Acbd3 recombinant protein
[Similar Products]
Product Synonym Gene Name
Acbd3[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
2-525aa, Full Length of Mature Protein
Sequence
AAQLNVEQLE VSLDGLTLSP DSEERPGAEG APPQTPPSSA PGNGLGSGAS GQQREPGEAA AEGAAEEARR MEQHWGFGLE ELYGLALRFY KIKDGKAFHP TYEEKLKFVA LHKQVLLGPY NPDTSPEVGF FDVLGNDRRR EWAALGNMSK EDAMVEFVKL LNKCCPLLSA YVASHRIEKE EEEKRRKAEE ERRQREEEER ERLQKEEEKR KREKEDRLRR EEEERRRIEE ERLRLEQQKQ QIMAALNSQT AVQFQQYAAQ QYPGNYEQQQ ILIRQLQEQH YQQYMQQLYQ VQLAQQQAAL QKQQEVVMAG ASLPASSKVN TAGASDTLSV NGQAKTHTEN SEKVLEPEAA EEALENGPKD SLPVIAAPSM WTRPQIKDFK EKIRQDADSV ITVRRGEVVT VRVPTHEEGS YLFWEFATDS YDIGFGVYFE WTDSPNAAVS VHVSESSDEE EEEEENVTCE EKAKKNANKP LLDEIVPVYR RDCHEEVYAG SHQYPGRGVY LLKFDNSYSL WRSKSVYYRV YYTR
3D Structure
ModBase 3D Structure for Q8BMP6
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Storage Buffer
Tris-based buffer, 50% glycerol
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of Acbd3 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
Acbd3 recombinant protein
The Golgi complex plays a key role in the sorting and modification of proteins exported from the endoplasmic reticulum. This protein is involved in the maintenance of Golgi structure and function through its interaction with the integral membrane protein giantin. It may also be involved in the hormonal regulation of steroid formation.
NCBI/Uniprot data below describe general gene information for Acbd3. It may not necessarily be applicable to this product.
NCBI Accession #
NP_573488.2
[Other Products]
NCBI GenBank Nucleotide #
NM_133225.3
[Other Products]
UniProt Primary Accession #
Q8BMP6
[Other Products]
UniProt Secondary Accession #
O35371[Other Products]
UniProt Related Accession #
Q8BMP6[Other Products]
Molecular Weight
60,181 Da
NCBI Official Full Name
Golgi resident protein GCP60
NCBI Official Synonym Full Names
acyl-Coenzyme A binding domain containing 3
NCBI Official Symbol
Acbd3??[Similar Products]
NCBI Official Synonym Symbols
Pap7; 60kDa; GCP60; GOLPH1; Gocap1; D1Ertd10e; 8430407O11Rik
??[Similar Products]
NCBI Protein Information
Golgi resident protein GCP60
UniProt Protein Name
Golgi resident protein GCP60
UniProt Synonym Protein Names
Acyl-CoA-binding domain-containing protein 3; Golgi complex-associated protein 1; GOCAP1; Golgi phosphoprotein 1; GOLPH1; PBR- and PKA-associated protein 7; Peripheral benzodiazepine receptor-associated protein PAP7
Protein Family
Golgi resident protein
UniProt Gene Name
Acbd3??[Similar Products]
UniProt Synonym Gene Names
Gcp60; Pap7; GOCAP1; GOLPH1??[Similar Products]
UniProt Comments for Acbd3
Involved in the maintenance of Golgi structure by interacting with giantin, affecting protein transport between the endoplasmic reticulum and Golgi (). Involved in hormone-induced steroid biosynthesis in testicular Leydig cells (PubMed:12711385). Recruits PI4KB to the Golgi apparatus membrane; enhances the enzyme activity of PI4KB activity via its membrane recruitment thereby increasing the local concentration of the substrate in the vicinity of the kinase ().
Research Articles on Acbd3
1. these findings suggest that ACBD3 has prominent impacts on cellular NAD(+) metabolism via regulating PARP1 activation-dependent auto-modification and thus cell metabolism and function.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
