Product Name
Putative tRNA (FTSJ1), Polyclonal Antibody
Full Product Name
Rabbit anti-human Putative tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase polyclonal Antibody, FITC
Product Synonym Names
2'-O-ribose RNA methyltransferase TRM7 homolog Protein ftsJ homolog 1 FTSJ1 JM23
Product Gene Name
anti-FTSJ1 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q9UET6
Purity/Purification
Caprylic Acid Ammonium Sulfate Precipitation Purified
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Immunogen
Recombinant human Putative tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase protein
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-133596
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of anti-FTSJ1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-FTSJ1 antibody
ELISA (EIA)
NCBI/Uniprot data below describe general gene information for FTSJ1. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001269086.1
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NCBI GenBank Nucleotide #
NM_001282157.1
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UniProt Primary Accession #
Q9UET6
[Other Products]
UniProt Secondary Accession #
O75670; B2RCJ0[Other Products]
UniProt Related Accession #
Q9UET6[Other Products]
Molecular Weight
35,867 Da[Similar Products]
NCBI Official Full Name
putative tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase isoform c
NCBI Official Synonym Full Names
FtsJ RNA methyltransferase homolog 1 (E. coli)
NCBI Official Symbol
FTSJ1??[Similar Products]
NCBI Official Synonym Symbols
JM23; MRX9; SPB1; CDLIV; MRX44; TRMT7
??[Similar Products]
NCBI Protein Information
putative tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase
UniProt Protein Name
Putative tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase
UniProt Synonym Protein Names
2'-O-ribose RNA methyltransferase TRM7 homolog
Protein Family
Putative tRNA-binding protein
UniProt Gene Name
FTSJ1??[Similar Products]
UniProt Entry Name
TRM7_HUMAN
NCBI Summary for FTSJ1
This gene encodes a member of the methyltransferase superfamily. The encoded protein localizes to the nucleolus, binds to S-adenosylmethionine, and may be involved in the processing and modification of ribosomal RNA. Mutations in this gene are associated with mental retardation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
UniProt Comments for FTSJ1
FTSJ1: Defects in FTSJ1 are the cause of mental retardation X- linked type 44 (MRX44). Mental retardation is characterized by significantly sub-average general intellectual functioning associated with impairments in adaptative behavior and manifested during the developmental period. Non-syndromic mental retardation patients do not manifest other clinical signs. Belongs to the methyltransferase superfamily. RlmE family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Methyltransferase; EC 2.1.1.205
Chromosomal Location of Human Ortholog: Xp11.23
Cellular Component: cytoplasm
Molecular Function: tRNA methyltransferase activity
Biological Process: tRNA methylation
Disease: Mental Retardation, X-linked 9
Research Articles on FTSJ1
1. These findings suggest that genetic variations in FtsJ homolog 1 (E. coli) possibly influence human cognitive ability.
Precautions
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Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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