Product Name
3-hydroxyacyl-CoA dehydratase 3 (PTPLAD1), Recombinant Protein
Full Product Name
Recombinant Pongo abelii 3-hydroxyacyl-CoA dehydratase 3 (PTPLAD1)
Product Gene Name
PTPLAD1 recombinant protein
[Similar Products]
Product Synonym Gene Name
HACD3[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
1-364aa; full length protein
Sequence
MAMENQVLTP HVYWAQRHRE LYLRVELSDV QNPAISTTEN VLHFKAQGHG AKGDNVYEFH LEFLDLVKPE PVYKLTQRQV NITVQKKVSQ WWERLTKQEK RPLFLAPDFD RWLDESDAEM ELRAKEEERL NKLRLESEGS PETLTNLRKG YLFMYNLVQF LGFSWIFVNL TVRFCILGKE SFYDTFHTVA DMMYFCQMLA VVETINAAIG VTTSPVLPSL IQLLGRNFIL FIIFGTMEEM QNKAVVFFVF YLWSAIEIFR YSFYMLTCID MDWEVLTWLR YTLWIPLYPL GCLAEAVSVV QSIPIFNETG RFSFTLPYPV KIKVRFSFFL QIYLIMIFLG LYINFRHLYK QRRRRYGQKK KKIH
3D Structure
ModBase 3D Structure for Q5NVQ2
Host
Cell Free Expression
Form/Format
Liquid containing glycerol
Species
Pongo abelii (Sumatran orangutan)
Storage Buffer
Tris-based buffer, 50% glycerol.
Preparation and Storage
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
Repeated freezing and thawing is not recommended. Store working aliquots at 4 degree C for up to one week.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of PTPLAD1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Product Categories/Family for PTPLAD1 recombinant protein
Transmembrane Protein
Application Notes for PTPLAD1 recombinant protein
This is a recombinant transmembrane protein expressed in a cell-free expression system.
NCBI/Uniprot data below describe general gene information for PTPLAD1. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001127566.1
[Other Products]
NCBI GenBank Nucleotide #
NM_001134094.1
[Other Products]
UniProt Primary Accession #
Q5NVQ2
[Other Products]
UniProt Secondary Accession #
Q5R6L7[Other Products]
UniProt Related Accession #
Q5NVQ2[Other Products]
Molecular Weight
43,337 Da
NCBI Official Full Name
very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3
NCBI Official Symbol
PTPLAD1??[Similar Products]
NCBI Official Synonym Symbols
HACD3
??[Similar Products]
NCBI Protein Information
very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3
UniProt Protein Name
Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3
UniProt Synonym Protein Names
3-hydroxyacyl-CoA dehydratase 3Curated; HACD3Curated; Protein-tyrosine phosphatase-like A domain-containing protein 1Curated
UniProt Gene Name
HACD3??[Similar Products]
UniProt Synonym Gene Names
PTPLAD1Curated; HACD3Curated??[Similar Products]
UniProt Entry Name
HACD3_PONAB
UniProt Comments for PTPLAD1
Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates in the production of VLCFAs of different chain lengths that are involved in multiple
biological processes as precursors of membrane lipids and lipid mediators. Involved in Rac1-signaling pathways leading to the modulation of gene expression.
Precautions
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Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
