Product Name
GTP-Binding Protein SAR1B, Recombinant Protein
Popular Item
Full Product Name
Recombinant Human GTP-Binding Protein SAR1B
Product Synonym Names
SAR1B Human; GTP-Binding Protein SAR1B Human Recombinant; GTP-binding protein SAR1b; GTP-binding protein B; GTBPB; SAR1B; SARA2; SARB; ANDD; CMRD
Product Gene Name
SAR1B recombinant protein
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Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
MGSSHHH HHH SSGLVPRGSH MGSMSF IFDW IYSGFSSVLQ FLGLYKKTGK LVFLGLDNAG KTTLLHMLKD DRLGQHVPTL HPTSEELTIA GMTFTTFDLG GHVQARRVWK NYLPAINGIV FLVDCADHER LLESKEELDS LMTDETIANV PILILGNKID RPEAISEERL REMFGLYGQT TGKGSISLKE LNARPLEVFM CSVLKRQGYG EGFRWMAQYI D.
3D Structure
ModBase 3D Structure for Q9Y6B6
Purity/Purification
Greater than 95.0% as determined by SDS-PAGE.
Form/Format
SAR1B protein solution (0.5mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 0.15M NaCl and 10% glycerol.
Sterile Filtered colorless solution.
Preparation and Storage
Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at -20 degree C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Other Notes
Small volumes of SAR1B recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
SAR1B recombinant protein
Description: SAR1B Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 221 amino acids (1-198 a.a) and having a molecular mass of 24.8kDa.SAR1B is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Introduction: SAR1B is a small GTPase that functions as a homodimer. GTP-Binding Protein SAR1B (SAR1b) is involved in transport from the endoplasmic reticulum to the Golgi apparatus and also in the selection of the protein cargo and the assembly of the COPII coat complex. The SAR1B protein is activated by the guanine nucleotide exchange factor PREB. SAR1B gene defects are a cause of chylomicron retention disease (CMRD), also known as Anderson disease (ANDD).
Product Categories/Family for SAR1B recombinant protein
RECOMBINANT & NATURAL PROTEINS; Recombinant Proteins
NCBI/Uniprot data below describe general gene information for SAR1B. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001028675.1
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NCBI GenBank Nucleotide #
NM_001033503.2
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UniProt Primary Accession #
Q9Y6B6
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UniProt Secondary Accession #
Q567T4; D3DQA4[Other Products]
UniProt Related Accession #
Q9Y6B6[Other Products]
Molecular Weight
22,410 Da
NCBI Official Full Name
GTP-binding protein SAR1b
NCBI Official Synonym Full Names
secretion associated, Ras related GTPase 1B
NCBI Official Symbol
SAR1B??[Similar Products]
NCBI Official Synonym Symbols
ANDD; CMRD; GTBPB; SARA2
??[Similar Products]
NCBI Protein Information
GTP-binding protein SAR1b; 2310075M17Rik; GTP-binding protein B; GTP-binding protein Sara; SAR1 homolog B; SAR1a gene homolog 2
UniProt Protein Name
GTP-binding protein SAR1b
UniProt Synonym Protein Names
GTP-binding protein B; GTBPB
Protein Family
GTP-binding protein
UniProt Gene Name
SAR1B??[Similar Products]
UniProt Synonym Gene Names
SARA2; SARB; GTBPB??[Similar Products]
UniProt Entry Name
SAR1B_HUMAN
Precautions
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Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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