Full Product Name
PRLH Antibody (Center)
Product Synonym Names
Prolactin-releasing peptide; PrRP; Prolactin-releasing hormone; Prolactin-releasing peptide PrRP31; Prolactin-releasing peptide PrRP20; PRLH; PRH
Product Gene Name
anti-PRLH antibody
[Similar Products]
Antibody/Peptide Pairs
PRLH peptide (MBS9219701) is used for blocking the activity of PRLH antibody (MBS9210723)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Positions
27-56
3D Structure
ModBase 3D Structure for P81277
Specificity
This PRLH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 27-56 amino acids from the Central region of human PRLH.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.5 (lot specific)
Antigen Type
Synthetic Peptide
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Other Notes
Small volumes of anti-PRLH antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-PRLH antibody
Stimulates prolactin (PRL) release and regulates the expression of prolactin through its receptor GPR10. May stimulate lactotrophs directly to secrete PRL.
Applications Tested/Suitable for anti-PRLH antibody
Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC)
Application Notes for anti-PRLH antibody
WB~~1:1000
Western Blot (WB) of anti-PRLH antibody
PRLH Antibody (Center) western blot analysis in mouse Neuro-2a cell line lysates (35ug/lane).This demonstrates the PRLH antibody detected the PRLH protein (arrow).
Immunohistochemistry (IHC) of anti-PRLH antibody
PRLH Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of PRLH Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
NCBI/Uniprot data below describe general gene information for PRLH. It may not necessarily be applicable to this product.
NCBI Accession #
NP_056977.1
[Other Products]
NCBI GenBank Nucleotide #
NM_015893.1
[Other Products]
UniProt Primary Accession #
P81277
[Other Products]
UniProt Related Accession #
P81277[Other Products]
NCBI Official Full Name
prolactin-releasing peptide
NCBI Official Synonym Full Names
prolactin releasing hormone
NCBI Official Symbol
PRLH??[Similar Products]
NCBI Official Synonym Symbols
PRH; PRRP
??[Similar Products]
NCBI Protein Information
prolactin-releasing peptide
UniProt Protein Name
Prolactin-releasing peptide
UniProt Synonym Protein Names
Prolactin-releasing hormone
Protein Family
Prolactin-releasing peptide
UniProt Gene Name
PRLH??[Similar Products]
UniProt Synonym Gene Names
PRH; PrRP??[Similar Products]
UniProt Entry Name
PRRP_HUMAN
UniProt Comments for PRLH
PRLH: Stimulates prolactin (PRL) release and regulates the expression of prolactin through its receptor GPR10. May stimulate lactotrophs directly to secrete PRL.
Protein type: Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 2q37.3
Cellular Component: cytoplasm; extracellular region
Molecular Function: neuropeptide hormone activity; hormone activity; prolactin-releasing peptide receptor binding
Biological Process: fat cell differentiation; G-protein coupled receptor protein signaling pathway; autonomic nervous system development; tissue homeostasis; energy reserve metabolic process; response to glucose stimulus; regulation of multicellular organism growth; lipid metabolic process; reduction of food intake in response to dietary excess; response to insulin stimulus
Product References and Citations for anti-PRLH antibody
Lagerstrom, M.C., et al. Ann. N. Y. Acad. Sci. 1040, 368-370 (2005) :
Takahashi, K., et al. Peptides 23(6):1135-1140(2002)
Yasui, Y., et al. Endocr. J. 48(3):397-401(2001)
Langmead, C.J., et al. Br. J. Pharmacol. 131(4):683-688(2000)
Zhang, X., et al. J. Clin. Endocrinol. Metab. 84(12):4652-4655(1999)
Research Articles on PRLH
1. Review discusses the ancestral relationship between prolactin-releasing hormone and the C-terminal RF-motif amide precursor peptide (C-RF).
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
