Product Name
Rho GDP-dissociation inhibitor 3 (Arhgdig), Recombinant Protein
Full Product Name
Recombinant Mouse Rho GDP-dissociation inhibitor 3 (Arhgdig)
Product Gene Name
Arhgdig recombinant protein
[Similar Products]
Product Synonym Gene Name
Arhgdig[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
1-225aa, full length protein
Sequence
MLGLDACELG EQLLELLRLA LCARVLLADK DGESTPSDEV LDEIVPEYQA PGKKSMLAIW QLDPGDVSLV KYKQALLGPL PPIMDPSLPN VQVTRLTLLT EQAPGPIIMD LTGDLDALKN QVFVLKEGIE YKVKITFKVN KEIVSGLKCL HHTYRRGLRV DKAIFMVGSY GPRAQEYEFV TSVEEAPRGA LARGLYVVRS LFTDDDRLNH LSWEWHLHVC QDWKD
3D Structure
ModBase 3D Structure for Q62160
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Storage Buffer
Tris-based buffer, 50% glycerol
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of Arhgdig recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for Arhgdig. It may not necessarily be applicable to this product.
NCBI Accession #
NP_032139.1
[Other Products]
NCBI GenBank Nucleotide #
NM_008113.3
[Other Products]
UniProt Primary Accession #
Q62160
[Other Products]
UniProt Related Accession #
Q62160[Other Products]
Molecular Weight
25,296 Da
NCBI Official Full Name
rho GDP-dissociation inhibitor 3
NCBI Official Synonym Full Names
Rho GDP dissociation inhibitor (GDI) gamma
NCBI Official Symbol
Arhgdig??[Similar Products]
NCBI Official Synonym Symbols
Gdi5; RIP2; Rho-GDI2; Rho-GDI-3
??[Similar Products]
NCBI Protein Information
rho GDP-dissociation inhibitor 3
UniProt Protein Name
Rho GDP-dissociation inhibitor 3
UniProt Synonym Protein Names
Rho-GDI gamma; Rho-GDI2
Protein Family
Rho GDP-dissociation inhibitor
UniProt Gene Name
Arhgdig??[Similar Products]
UniProt Synonym Gene Names
Gdi5; Rho GDI 3??[Similar Products]
UniProt Comments for Arhgdig
Inhibits GDP/GTP exchange reaction of RhoB. Interacts specifically with the GDP- and GTP-bound forms of post-translationally processed Rhob and Rhog proteins, both of which show a growth-regulated expression in mammalian cells. Stimulates the release of the GDP-bound but not the GTP-bound RhoB protein. Also inhibits the GDP/GTP exchange of RhoB but shows less ability to inhibit the dissociation of prebound GTP.
Research Articles on Arhgdig
1. RhoGDI2 is required for PKB and CREB activation and cdc42 expression in astrocyte migration after kainic acid-mediated excitotoxic lesion in mouse brain.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
