Product Name
TALDO1, Polyclonal Antibody
Full Product Name
TALDO1 Polyclonal Antibody
Product Synonym Names
TAL; TAL-H; TALDOR; TALH
Product Gene Name
anti-TALDO1 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence
MSSSPVKRQR MESALDQLKQ FTTVVADTGD FHAIDEYKPQ DATTNPSLIL AAAQMPAYQE LVEEAIAYGR KLGGSQEDQI KNAIDKLFVL FGAEILKKIP GRVSTEVDAR LSFDKDAMVA RARRLIELYK EAGISKDRIL IKLSSTWEGI QAGKELEEQH GIHCNMTLLF SFAQAVACAE AGVTLISPFV GRILDWHVAN TDKKSYEPLE DPGVKSVTKI YNYYKKFSYK TIVMGASFRN TGEIKALAGC DFLTI
3D Structure
ModBase 3D Structure for P37837
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Affinity Purification
Immunogen
Recombinant protein of human TALDO1
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Cellular Location
Cytoplasm
Positive Samples
293T, A-431, HL-60, SW480, Mouse brain, Mouse kidney, Rat liver, Rat brain
Preparation and Storage
Store at -20 degree C. Avoid freeze / thaw cycles.
Other Notes
Small volumes of anti-TALDO1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-TALDO1 antibody
Transaldolase 1 is a key enzyme of the nonoxidative pentose phosphate pathway providing ribose-5-phosphate for nucleic acid synthesis and NADPH for lipid biosynthesis. This pathway can also maintain glutathione at a reduced state and thus protect sulfhydryl groups and cellular integrity from oxygen radicals. The functional gene of transaldolase 1 is located on chromosome 11 and a pseudogene is identified on chromosome 1 but there are conflicting map locations. The second and third exon of this gene were developed by insertion of a retrotransposable element. This gene is thought to be involved in multiple sclerosis.
Product Categories/Family for anti-TALDO1 antibody
Polyclonal Antibodies
Applications Tested/Suitable for anti-TALDO1 antibody
Western Blot (WB)
Application Notes for anti-TALDO1 antibody
WB: 1:500 - 1:2000
Western Blot (WB) of anti-TALDO1 antibody
Western blot analysis of extracts of various cell lines, using TALDO1 antibody at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit.
Exposure time: 30s.
NCBI/Uniprot data below describe general gene information for TALDO1. It may not necessarily be applicable to this product.
NCBI Accession #
NP_006746.1
[Other Products]
NCBI GenBank Nucleotide #
NM_006755.1
[Other Products]
UniProt Primary Accession #
P37837
[Other Products]
UniProt Secondary Accession #
O00751; Q8WV32; Q8WZ45; B2R8M2[Other Products]
UniProt Related Accession #
P37837[Other Products]
Molecular Weight
Calculated: 37kDa
Observed: 38kDa
NCBI Official Full Name
transaldolase
NCBI Official Synonym Full Names
transaldolase 1
NCBI Official Symbol
TALDO1??[Similar Products]
NCBI Official Synonym Symbols
TAL; TALH; TAL-H; TALDOR
??[Similar Products]
NCBI Protein Information
transaldolase
UniProt Protein Name
Transaldolase
Protein Family
Transaldolase
UniProt Gene Name
TALDO1??[Similar Products]
UniProt Synonym Gene Names
TAL; TALDO; TALDOR??[Similar Products]
NCBI Summary for TALDO1
Transaldolase 1 is a key enzyme of the nonoxidative pentose phosphate pathway providing ribose-5-phosphate for nucleic acid synthesis and NADPH for lipid biosynthesis. This pathway can also maintain glutathione at a reduced state and thus protect sulfhydryl groups and cellular integrity from oxygen radicals. The functional gene of transaldolase 1 is located on chromosome 11 and a pseudogene is identified on chromosome 1 but there are conflicting map locations. The second and third exon of this gene were developed by insertion of a retrotransposable element. This gene is thought to be involved in multiple sclerosis. [provided by RefSeq, Jul 2008]
UniProt Comments for TALDO1
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
Research Articles on TALDO1
1. The above findings support the premise that biallelic mutations in TALDO1 are responsible for transaldolase deficiency and confirm the broad phenotypic variability of this condition, even with the same genotype.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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