Product Name
TALDO1, cDNA Clone
Full Product Name
TALDO1 cDNA Clone
Product Gene Name
TALDO1 cdna clone
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
atgtcgagct cacccgtgaa gcgtcagagg atggagtccg cgctggacca gctcaagcag ttcaccaccg tggtggccga cacgggcgac ttccacgcca tcgacgagta caagccccag gatgctacca ccaacccgtc cctgatcctg gccgcagcac agatgcccgc ttaccaggag ctggtggagg aggcgattgc ctatggccgg aagctgggcg ggtcacaaga ggaccagatt aaaaatgcta ttgataaact ttttgtgttg tttggagcag aaatactaaa gaagattccg ggccgagtat ccacagaagt agacgcaagg ctctcctttg ataaagatgc gatggtggcc agagccaggc ggctcatcga gctctacaag gaagctggga tcagcaagga ccgaattctt ataaagctgt catcaacctg ggaaggaatt caggctggaa aggagctcga ggagcagcac ggcatccact gcaacatgac gttactcttc tccttcgccc aggctgtggc ctgtgccgag gcgggtgtga ccctcatctc cccatttgtt gggcgcatcc ttgattggca tgtggcaaac accgacaaga aatcctatga gcccctggaa gaccctgggg taaagagtgt cactaaaatc tacaactact acaagaagtt tagctacaaa accattgtca tgggcgcctc cttccgcaac acgggcgaga tcaaagcact ggccggctgt gacttcctca ccatctcacc caagctcctg ggagagctgc tgcaggacaa cgccaagctg gtgcctgtgc tctcagccaa ggcggcccaa gccagtgacc tggaaaaaat ccacctggat gagaagtctt tccgttggtt gcacaacgag gaccagatgg ctgtggagaa gctctctgac gggatccgca agtttgccgc tgatgcagtg aagctggagc ggatgctgac agaacgaatg ttcaatgcag agaatggaaa gtag
Clone Sequence Report
Provided with product shipment
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of TALDO1 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for TALDO1. It may not necessarily be applicable to this product.
NCBI Accession #
BC010103
[Other Products]
UniProt Secondary Accession #
O00751; Q8WV32; Q8WZ45; B2R8M2[Other Products]
UniProt Related Accession #
P37837[Other Products]
Molecular Weight
37,540 Da
NCBI Official Full Name
Homo sapiens transaldolase 1, mRNA
NCBI Official Synonym Full Names
transaldolase 1
NCBI Official Symbol
TALDO1??[Similar Products]
NCBI Official Synonym Symbols
TAL; TALH; TAL-H; TALDOR
??[Similar Products]
NCBI Protein Information
transaldolase
UniProt Protein Name
Transaldolase
Protein Family
Transaldolase
UniProt Gene Name
TALDO1??[Similar Products]
UniProt Synonym Gene Names
TAL; TALDO; TALDOR??[Similar Products]
UniProt Entry Name
TALDO_HUMAN
NCBI Summary for TALDO1
Transaldolase 1 is a key enzyme of the nonoxidative pentose phosphate pathway providing ribose-5-phosphate for nucleic acid synthesis and NADPH for lipid biosynthesis. This pathway can also maintain glutathione at a reduced state and thus protect sulfhydryl groups and cellular integrity from oxygen radicals. The functional gene of transaldolase 1 is located on chromosome 11 and a pseudogene is identified on chromosome 1 but there are conflicting map locations. The second and third exon of this gene were developed by insertion of a retrotransposable element. This gene is thought to be involved in multiple sclerosis. [provided by RefSeq, Jul 2008]
UniProt Comments for TALDO1
TALDO1: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. Defects in TALDO1 are the cause of transaldolase 1 deficiency (TALDO1 deficiency). It results in telangiectases of the skin, hepatosplenomegaly, and enlarged clitoris. Belongs to the transaldolase family. Type 1 subfamily.
Protein type: Carbohydrate Metabolism - pentose phosphate pathway; Transferase; EC 2.2.1.2
Chromosomal Location of Human Ortholog: 11p15.5-p15.4
Cellular Component: cytoplasm; cytosol; nucleus
Molecular Function: protein binding; transaldolase activity
Biological Process: carbohydrate metabolic process; pentose-phosphate shunt; xylulose biosynthetic process
Disease: Transaldolase Deficiency
Research Articles on TALDO1
1. The above findings support the premise that biallelic mutations in TALDO1 are responsible for transaldolase deficiency and confirm the broad phenotypic variability of this condition, even with the same genotype.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
