Product Name
Major facilitator superfamily domain-containing protein 8 (MFSD8), Recombinant Protein
Full Product Name
Recombinant Human Major facilitator superfamily domain-containing protein 8 (MFSD8), partial
Product Gene Name
MFSD8 recombinant protein
[Similar Products]
Product Synonym Gene Name
MFSD8[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q8NHS3
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Species
Homo sapiens (Human)
Storage Buffer
Tris-based buffer, 50% glycerol
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of MFSD8 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for MFSD8. It may not necessarily be applicable to this product.
NCBI Accession #
NP_689991.1
[Other Products]
NCBI GenBank Nucleotide #
NM_152778.2
[Other Products]
UniProt Primary Accession #
Q8NHS3
[Other Products]
UniProt Secondary Accession #
Q8N2P3; B2RDM1; B7Z205[Other Products]
UniProt Related Accession #
Q8NHS3[Other Products]
Molecular Weight
17,092 Da
NCBI Official Full Name
major facilitator superfamily domain-containing protein 8
NCBI Official Synonym Full Names
major facilitator superfamily domain containing 8
NCBI Official Symbol
MFSD8??[Similar Products]
NCBI Official Synonym Symbols
CCMD; CLN7
??[Similar Products]
NCBI Protein Information
major facilitator superfamily domain-containing protein 8
UniProt Protein Name
Major facilitator superfamily domain-containing protein 8
UniProt Synonym Protein Names
Ceroid-lipofuscinosis neuronal protein 7
Protein Family
Major facilitator superfamily domain-containing protein
UniProt Gene Name
MFSD8??[Similar Products]
UniProt Synonym Gene Names
CLN7??[Similar Products]
NCBI Summary for MFSD8
This gene encodes a ubiquitous integral membrane protein that contains a transporter domain and a major facilitator superfamily (MFS) domain. Other members of the major facilitator superfamily transport small solutes through chemiosmotic ion gradients. The substrate transported by this protein is unknown. The protein likely localizes to lysosomal membranes. Mutations in this gene are correlated with a variant form of late infantile-onset neuronal ceroid lipofuscinoses (vLINCL). [provided by RefSeq, Oct 2008]
UniProt Comments for MFSD8
May be a carrier that transport small solutes by using chemiosmotic ion gradients.
Research Articles on MFSD8
1. This study highlights a hierarchy of MFSD8 variant severity, predicting three consequences of mutation: (1) nonsyndromic localized maculopathy, (2) nonsyndromic widespread retinopathy, or (3) syndromic neurological disease.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
