Product Name
MFSD8, Blocking Peptide
Full Product Name
MFSD8 Peptide - middle region
Product Gene Name
MFSD8 blocking peptide
[Similar Products]
Product Synonym Gene Name
CLN7; MGC33302[Similar Products]
MFSD8 peptide (MBS3237227) is used for blocking the activity of MFSD8 antibody (MBS3212280)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
FFILLPWGNQ FPKIQWEDLH NNSIPNTTFG EIIIGLWKSP MEDDNERPTG
3D Structure
ModBase 3D Structure for Q8NHS3
Form/Format
Lyophilized powder
Preparation and Storage
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20 degree C. Avoid repeat freeze-thaw cycles.
Other Notes
Small volumes of MFSD8 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
MFSD8 blocking peptide
This is a synthetic peptide designed for use in combination with anti-MFSD8 Antibody, made
Target Description: This gene encodes a ubiquitous integral membrane protein that contains a transporter domain and a major facilitator superfamily (MFS) domain. Other members of the major facilitator superfamily transport small solutes through chemiosmotic ion gradients. The substrate transported by this protein is unknown. The protein likely localizes to lysosomal membranes. Mutations in this gene are correlated with a variant form of late infantile-onset neuronal ceroid lipofuscinoses (vLINCL).
Product Categories/Family for MFSD8 blocking peptide
Peptide
Applications Tested/Suitable for MFSD8 blocking peptide
Western Blot (WB)
NCBI/Uniprot data below describe general gene information for MFSD8. It may not necessarily be applicable to this product.
NCBI Accession #
NP_689991
[Other Products]
NCBI GenBank Nucleotide #
NM_152778
[Other Products]
UniProt Primary Accession #
Q8NHS3
[Other Products]
UniProt Related Accession #
Q8NHS3[Other Products]
NCBI Official Full Name
major facilitator superfamily domain-containing protein 8 isoform 1
NCBI Official Synonym Full Names
major facilitator superfamily domain containing 8
NCBI Official Symbol
MFSD8??[Similar Products]
NCBI Official Synonym Symbols
CCMD; CLN7
??[Similar Products]
NCBI Protein Information
major facilitator superfamily domain-containing protein 8
UniProt Protein Name
Major facilitator superfamily domain-containing protein 8
UniProt Synonym Protein Names
Ceroid-lipofuscinosis neuronal protein 7
Protein Family
Major facilitator superfamily domain-containing protein
UniProt Gene Name
MFSD8??[Similar Products]
UniProt Synonym Gene Names
CLN7??[Similar Products]
UniProt Entry Name
MFSD8_HUMAN
NCBI Summary for MFSD8
This gene encodes a ubiquitous integral membrane protein that contains a transporter domain and a major facilitator superfamily (MFS) domain. Other members of the major facilitator superfamily transport small solutes through chemiosmotic ion gradients. The substrate transported by this protein is unknown. The protein likely localizes to lysosomal membranes. Mutations in this gene are correlated with a variant form of late infantile-onset neuronal ceroid lipofuscinoses (vLINCL). [provided by RefSeq, Oct 2008]
Research Articles on MFSD8
1. Quantification revealed that the amounts of 12 different soluble lysosomal proteins were significantly reduced in Cln7 ko MEFs compared with wild-type controls. One of the most significantly depleted lysosomal proteins was Cln5 protein that underlies another distinct neuronal ceroid lipofuscinosis disorder
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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