Full Product Name
MFSD8 Polyclonal Antibody
Product Synonym Names
Major facilitator superfamily domain-containing protein 8; Ceroid-lipofuscinosis neuronal protein 7; MFSD8; CLN7
Product Gene Name
anti-MFSD8 antibody
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Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q8NHS3
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Immunogen
Synthesized peptide derived from human protein. at AA range: 351-400
Preparation and Storage
Store at-20 degree C for 1 year.
Other Notes
Small volumes of anti-MFSD8 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-MFSD8 antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-MFSD8 antibody
WB: 1:500-2000
ELISA: 1:5000-20000
NCBI/Uniprot data below describe general gene information for MFSD8. It may not necessarily be applicable to this product.
NCBI Accession #
NP_689991.1
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NCBI GenBank Nucleotide #
NM_152778.2
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UniProt Primary Accession #
Q8NHS3
[Other Products]
UniProt Secondary Accession #
Q8N2P3; B2RDM1; B7Z205[Other Products]
UniProt Related Accession #
Q8NHS3[Other Products]
NCBI Official Full Name
major facilitator superfamily domain-containing protein 8
NCBI Official Synonym Full Names
major facilitator superfamily domain containing 8
NCBI Official Symbol
MFSD8??[Similar Products]
NCBI Official Synonym Symbols
CCMD; CLN7
??[Similar Products]
NCBI Protein Information
major facilitator superfamily domain-containing protein 8
UniProt Protein Name
Major facilitator superfamily domain-containing protein 8
UniProt Synonym Protein Names
Ceroid-lipofuscinosis neuronal protein 7
Protein Family
Major facilitator superfamily domain-containing protein
UniProt Gene Name
MFSD8??[Similar Products]
UniProt Synonym Gene Names
CLN7??[Similar Products]
NCBI Summary for MFSD8
This gene encodes a ubiquitous integral membrane protein that contains a transporter domain and a major facilitator superfamily (MFS) domain. Other members of the major facilitator superfamily transport small solutes through chemiosmotic ion gradients. The substrate transported by this protein is unknown. The protein likely localizes to lysosomal membranes. Mutations in this gene are correlated with a variant form of late infantile-onset neuronal ceroid lipofuscinoses (vLINCL). [provided by RefSeq, Oct 2008]
UniProt Comments for MFSD8
May be a carrier that transport small solutes by using chemiosmotic ion gradients.
Research Articles on MFSD8
1. This study highlights a hierarchy of MFSD8 variant severity, predicting three consequences of mutation: (1) nonsyndromic localized maculopathy, (2) nonsyndromic widespread retinopathy, or (3) syndromic neurological disease.
Precautions
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Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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