Product Name
Transaldolase (TALDO1), Polyclonal Antibody
Full Product Name
Rabbit anti-human Transaldolase polyclonal Antibody, HRP conjugated
Product Gene Name
anti-TALDO1 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for P37837
Purity/Purification
Caprylic Acid Ammonium Sulfate Precipitation Purified
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Immunogen
Recombinant human Transaldolase protein
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-51439 / sc-51440 / sc-134795
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of anti-TALDO1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-TALDO1 antibody
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
Applications Tested/Suitable for anti-TALDO1 antibody
ELISA (EIA)
NCBI/Uniprot data below describe general gene information for TALDO1. It may not necessarily be applicable to this product.
NCBI Accession #
NP_006746.1
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NCBI GenBank Nucleotide #
NM_006755.1
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UniProt Primary Accession #
P37837
[Other Products]
UniProt Secondary Accession #
O00751; Q8WV32; Q8WZ45; B2R8M2[Other Products]
UniProt Related Accession #
P37837[Other Products]
Molecular Weight
37,540 Da[Similar Products]
NCBI Official Full Name
transaldolase
NCBI Official Synonym Full Names
transaldolase 1
NCBI Official Symbol
TALDO1??[Similar Products]
NCBI Official Synonym Symbols
TAL; TALH; TAL-H; TALDOR
??[Similar Products]
NCBI Protein Information
transaldolase
UniProt Protein Name
Transaldolase
Protein Family
Transaldolase
UniProt Gene Name
TALDO1??[Similar Products]
UniProt Synonym Gene Names
TAL; TALDO; TALDOR??[Similar Products]
UniProt Entry Name
TALDO_HUMAN
NCBI Summary for TALDO1
Transaldolase 1 is a key enzyme of the nonoxidative pentose phosphate pathway providing ribose-5-phosphate for nucleic acid synthesis and NADPH for lipid biosynthesis. This pathway can also maintain glutathione at a reduced state and thus protect sulfhydryl groups and cellular integrity from oxygen radicals. The functional gene of transaldolase 1 is located on chromosome 11 and a pseudogene is identified on chromosome 1 but there are conflicting map locations. The second and third exon of this gene were developed by insertion of a retrotransposable element. This gene is thought to be involved in multiple sclerosis. [provided by RefSeq, Jul 2008]
UniProt Comments for TALDO1
TALDO1: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. Defects in TALDO1 are the cause of transaldolase 1 deficiency (TALDO1 deficiency). It results in telangiectases of the skin, hepatosplenomegaly, and enlarged clitoris. Belongs to the transaldolase family. Type 1 subfamily.
Protein type: EC 2.2.1.2; Transferase; Carbohydrate Metabolism - pentose phosphate pathway
Chromosomal Location of Human Ortholog: 11p15.5-p15.4
Cellular Component: cytoplasm; cytosol; nucleus
Molecular Function: monosaccharide binding; protein binding; transaldolase activity
Biological Process: carbohydrate metabolic process; energy reserve metabolic process; fructose 6-phosphate metabolic process; pentose-phosphate shunt; pentose-phosphate shunt, non-oxidative branch; xylulose biosynthetic process
Disease: Transaldolase Deficiency
Research Articles on TALDO1
1. This study expands the clinical definition of transaldolase deficiency, and adds to its allelic heterogeneity.
Precautions
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Disclaimer
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