COL5A2; Collagen alpha-2, V chain

For Research Use Only. Not for use in diagnostic procedures.

Polyclonal

IgG

Rabbit

COL5A2 Polyclonal Antibody detects endogenous levels of COL5A2 protein.

>=90% by SDS-PAGE
Affinity purified by Protein A.

Lyophilized or Liquid

1 mg/mL (lot specific)

Upon delivery aliquot and store at -20 degree C for one year. Avoid repeated freeze/thaw cycles.
The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20 degree C.
When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-8 degree C.

Small volumes of anti-COL5A2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Western Blot (WB), Immunohistochemistry (IHC) Paraffin, ELISA (EIA)

WB: 1:500-2000
IHC-p: 1:100-300
ELISA: 1:20000

145 kDa

collagen type V alpha 2 chain

collagen alpha-2(V) chain

Collagen alpha-2(V) chain

This gene encodes an alpha chain for one of the low abundance fibrillar collagens. Fibrillar collagen molecules are trimers that can be composed of one or more types of alpha chains. Type V collagen is found in tissues containing type I collagen and appears to regulate the assembly of heterotypic fibers composed of both type I and type V collagen. This gene product is closely related to type XI collagen and it is possible that the collagen chains of types V and XI constitute a single collagen type with tissue-specific chain combinations. Mutations in this gene are associated with Ehlers-Danlos syndrome, types I and II. [provided by RefSeq, Jul 2008]

Type V collagen is a member of group I collagen (fibrillar forming collagen). It is a minor connective tissue component of nearly ubiquitous distribution. Type V collagen binds to DNA, heparan sulfate, thrombospondin, heparin, and insulin. Type V collagen is a key determinant in the assembly of tissue-specific matrices ().

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