ANPRB; Atrial natriuretic peptide receptor type B; Guanylate cyclase B; ANP-B; GC-B

For Research Use Only. Not for use in diagnostic procedures.

E Coli

>95% by SDS-PAGE

Liquid

Store at -20 degree C.
Avoid repeated freezing and thawing.

Small volumes of NPR2 protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

ELISA (EIA), Western Blot (WB), Affinity Purification (AP), Protein Array

111,208 Da

natriuretic peptide receptor 2

atrial natriuretic peptide receptor 2

Atrial natriuretic peptide receptor 2

ANPRB; ANP-B; ANPR-B; NPR-B; GC-B??[Similar Products]

This gene encodes natriuretic peptide receptor B, one of two integral membrane receptors for natriuretic peptides. Both NPR1 and NPR2 contain five functional domains: an extracellular ligand-binding domain, a single membrane-spanning region, and intracellularly a protein kinase homology domain, a helical hinge region involved in oligomerization, and a carboxyl-terminal guanylyl cyclase catalytic domain. The protein is the primary receptor for C-type natriuretic peptide (CNP), which upon ligand binding exhibits greatly increased guanylyl cyclase activity. Mutations in this gene are the cause of acromesomelic dysplasia Maroteaux type. [provided by RefSeq, Jul 2008]

Receptor for the C-type natriuretic peptide NPPC/CNP hormone. Has guanylate cyclase activity upon binding of its ligand. May play a role in the regulation of skeletal growth.

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