Product Name
Ferritin, Spleen (FTL), Protein
Full Product Name
Ferritin, Spleen, Human
Product Gene Name
FTL protein
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Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Chromosome Location
Chromosome: 10; NC_009153.2 (18929521..18930451). Location: chromosome: 10
3D Structure
ModBase 3D Structure for P02791
Purity/Purification
Highly Purified
90% (Iodination grade)
Form/Format
Supplied as a liquid in 15mM sodium chloride, pH 7.5.
Contaminants
None detected
Preparation and Storage
May be stored at 4 degree C. For long-term storage, aliquot and store at 4 degree C. Do not freeze. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer.
Other Notes
Small volumes of FTL protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Product Categories/Family for FTL protein
Molecular Biology; MB-Ferritin
Applications Tested/Suitable for FTL protein
ELISA (EL/EIA)
Application Notes for FTL protein
Suitable for use in ELISA.
NCBI/Uniprot data below describe general gene information for FTL. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001108012.1
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NCBI GenBank Nucleotide #
NM_001114540.1
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UniProt Primary Accession #
P02791
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UniProt Secondary Accession #
Q53VB4[Other Products]
UniProt Related Accession #
P02791[Other Products]
Molecular Weight
19,978 Da[Similar Products]
NCBI Official Full Name
ferritin light chain
NCBI Official Symbol
FTL??[Similar Products]
NCBI Official Synonym Symbols
FT
??[Similar Products]
NCBI Protein Information
ferritin light chain; ferritin L subunit
UniProt Protein Name
Ferritin light chain
UniProt Gene Name
FTL??[Similar Products]
UniProt Synonym Gene Names
Ferritin L subunit??[Similar Products]
UniProt Entry Name
FRIL_HORSE
UniProt Comments for FTL
Function: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney
By similarity.
Subunit structure: Oligomer of 24 subunits. There are two types of subunits: L (light) chain and H (heavy) chain. The major chain can be light or heavy, depending on the species and tissue type. The functional molecule forms a roughly spherical shell with a diameter of 12 nm and contains a central cavity into which the insoluble mineral iron core is deposited.
Miscellaneous: In horse spleen the light chain is the major chain.
Sequence similarities: Belongs to the ferritin family.Contains 1 ferritin-like diiron domain.
Research Articles on FTL
1. Transmission electron microscopy shows a clear selectivity of alkylated ferritin adsorption onto the PCL phase while wild ferritin predominantly adsorbs onto the PDTD phase.
Precautions
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Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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