Product Name
5'-nucleotidase (NT5E), Protein
Full Product Name
5'-nucleotidase
Product Synonym Names
NT5; NTE; Ecto-5'-nucleotidase; CD73
Product Gene Name
NT5E protein
[Similar Products]
Matching Pairs
Antibody: NT5E (MBS2891693)
Antigen: 5'-nucleotidase (MBS2888543)
Matching Pairs
Antibody: NT5E (MBS2891694)
Antigen: 5'-nucleotidase (MBS2888543)
Matching Pairs
Antibody: NT5E (MBS2891695)
Antigen: 5'-nucleotidase (MBS2888543)
Matching Pairs
Antibody: NT5E (MBS2891696)
Antigen: 5'-nucleotidase (MBS2888543)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
400-520aa
3D Structure
ModBase 3D Structure for P21589
Purity/Purification
>95% by SDS-PAGE
Endotoxin Level
<0.10 EU per 1 mug of the protein by the LAL method
Storage Buffer
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole,10%glycerol(PH8.0)
Preparation and Storage
Store at -20 degree C.
Avoid repeated freezing and thawing.
Other Notes
Small volumes of NT5E protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Product Categories/Family for NT5E protein
Cardiovascular
Applications Tested/Suitable for NT5E protein
ELISA (EIA), Western Blot (WB), Affinity Purification (AP), Protein Array
NCBI/Uniprot data below describe general gene information for NT5E. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001191742.1
[Other Products]
NCBI GenBank Nucleotide #
NM_001204813.1
[Other Products]
UniProt Primary Accession #
P21589
[Other Products]
UniProt Secondary Accession #
O75520; Q5W116; B3KQI8[Other Products]
UniProt Related Accession #
P21589[Other Products]
Molecular Weight
57,949 Da
NCBI Official Full Name
5'-nucleotidase isoform 2 preproprotein
NCBI Official Synonym Full Names
5'-nucleotidase ecto
NCBI Official Symbol
NT5E??[Similar Products]
NCBI Official Synonym Symbols
NT; eN; NT5; NTE; eNT; CD73; E5NT; CALJA
??[Similar Products]
NCBI Protein Information
5'-nucleotidase
UniProt Protein Name
5'-nucleotidase
UniProt Synonym Protein Names
Ecto-5'-nucleotidase; CD_antigen: CD73
Protein Family
5'-nucleotidase
UniProt Gene Name
NT5E??[Similar Products]
UniProt Synonym Gene Names
NT5; NTE; 5'-NT??[Similar Products]
NCBI Summary for NT5E
The protein encoded by this gene is a plasma membrane protein that catalyzes the conversion of extracellular nucleotides to membrane-permeable nucleosides. The encoded protein is used as a determinant of lymphocyte differentiation. Defects in this gene can lead to the calcification of joints and arteries. Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2011]
UniProt Comments for NT5E
Hydrolyzes extracellular nucleotides into membrane permeable nucleosides. Exhibits AMP-, NAD-, and NMN-nucleosidase activities.
Research Articles on NT5E
1. The Ecto-5'nucleotidase, together with alkaline phosphatase, also expressed apically in oviductal epithelium, complete the hydrolysis sequence by dephosphorylating AMP to adenosine.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
