5'-nucleotidase; 5'-NT; Ecto-5'-nucleotidase; NT5E; NT5; NTE; 3.1.3.5; CD73

For Research Use Only. Not for use in diagnostic procedures.

Store at 4 degree C

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Small volumes of NT5E elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS9425149 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the 5'-nucleotidase (NT5E) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing NT5E. The ELISA analytical biochemical technique of the MBS9425149 kit is based on NT5E antibody-NT5E antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect NT5E antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, NT5E. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

57,949 Da

5'-nucleotidase ecto

5'-nucleotidase

5'-nucleotidase

NT5; NTE; 5'-NT??[Similar Products]

The protein encoded by this gene is a plasma membrane protein that catalyzes the conversion of extracellular nucleotides to membrane-permeable nucleosides. The encoded protein is used as a determinant of lymphocyte differentiation. Defects in this gene can lead to the calcification of joints and arteries. Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2011]

NT5E: Hydrolyzes extracellular nucleotides into membrane permeable nucleosides. Homodimer; disulfide-linked. Belongs to the 5'-nucleotidase family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Cofactor and Vitamin Metabolism - nicotinate and nicotinamide; EC 3.1.3.5; Membrane protein, GPI anchor; Membrane protein, integral; Nucleotide Metabolism - purine; Nucleotide Metabolism - pyrimidine; Phosphatase (non-protein)

Chromosomal Location of Human Ortholog: 6q14.3

Cellular Component: cell surface; cytosol; membrane; plasma membrane

Molecular Function: 5'-nucleotidase activity

Biological Process: DNA metabolic process; leukocyte adhesion; NAD metabolic process; purine nucleotide catabolic process; pyrimidine nucleoside catabolic process

Disease: Calcification Of Joints And Arteries

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