Product Name
17beta-HSD4, Polyclonal Antibody
Full Product Name
17beta-HSD4 Polyclonal Antibody
Product Gene Name
anti-17beta-HSD4 antibody
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Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for P51659
Other Notes
Small volumes of anti-17beta-HSD4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for 17beta-HSD4. It may not necessarily be applicable to this product.
NCBI Accession #
NP_000405.1
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NCBI GenBank Nucleotide #
NM_000414.3
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UniProt Primary Accession #
P51659
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UniProt Secondary Accession #
B4DNV1; B4DVS5; E9PB82; F5HE57[Other Products]
UniProt Related Accession #
P51659[Other Products]
Molecular Weight
77,870 Da
NCBI Official Full Name
peroxisomal multifunctional enzyme type 2 isoform 2
NCBI Official Synonym Full Names
hydroxysteroid 17-beta dehydrogenase 4
NCBI Official Symbol
HSD17B4??[Similar Products]
NCBI Official Synonym Symbols
DBP; MFE-2; MPF-2; PRLTS1; SDR8C1
??[Similar Products]
NCBI Protein Information
peroxisomal multifunctional enzyme type 2
UniProt Protein Name
Peroxisomal multifunctional enzyme type 2
UniProt Synonym Protein Names
17-beta-hydroxysteroid dehydrogenase 4; 17-beta-HSD 4
UniProt Gene Name
HSD17B4??[Similar Products]
UniProt Synonym Gene Names
EDH17B4; SDR8C1; MFE-2; 17-beta-HSD 4; DBP; MPF-2??[Similar Products]
NCBI Summary for 17beta-HSD4
The protein encoded by this gene is a bifunctional enzyme that is involved in the peroxisomal beta-oxidation pathway for fatty acids. It also acts as a catalyst for the formation of 3-ketoacyl-CoA intermediates from both straight-chain and 2-methyl-branched-chain fatty acids. Defects in this gene that affect the peroxisomal fatty acid beta-oxidation activity are a cause of D-bifunctional protein deficiency (DBPD). An apparent pseudogene of this gene is present on chromosome 8. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014]
UniProt Comments for 17beta-HSD4
Bifunctional enzyme acting on the peroxisomal beta-oxidation pathway for fatty acids. Catalyzes the formation of 3-ketoacyl-CoA intermediates from both straight-chain and 2-methyl-branched-chain fatty acids.
Research Articles on 17beta-HSD4
1. This study reveals a crosstalk between acetylation and chaperone-mediated autophagy degradation in HSD17B4 regulation.
Precautions
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Disclaimer
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