Product Name
CAAX prenyl protease 1 homolog (ZMPSTE24), Recombinant Protein
Full Product Name
Recombinant Human CAAX prenyl protease 1 homolog (ZMPSTE24), partial
Product Gene Name
ZMPSTE24 recombinant protein
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for O75844
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Species
Homo sapiens (Human)
Storage Buffer
Tris-based buffer, 50% glycerol
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of ZMPSTE24 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for ZMPSTE24. It may not necessarily be applicable to this product.
NCBI Accession #
NP_005848.2
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NCBI GenBank Nucleotide #
NM_005857.4
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UniProt Primary Accession #
O75844
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UniProt Secondary Accession #
Q8NDZ8; Q9UBQ2; B3KQI7; D3DPU7[Other Products]
UniProt Related Accession #
O75844[Other Products]
Molecular Weight
54,813 Da
NCBI Official Full Name
CAAX prenyl protease 1 homolog
NCBI Official Synonym Full Names
zinc metallopeptidase STE24
NCBI Official Symbol
ZMPSTE24??[Similar Products]
NCBI Official Synonym Symbols
HGPS; PRO1; FACE1; STE24; FACE-1; Ste24p
??[Similar Products]
NCBI Protein Information
CAAX prenyl protease 1 homolog
UniProt Protein Name
CAAX prenyl protease 1 homolog
UniProt Synonym Protein Names
Farnesylated proteins-converting enzyme 1; FACE-1; Prenyl protein-specific endoprotease 1; Zinc metalloproteinase Ste24 homolog
UniProt Gene Name
ZMPSTE24??[Similar Products]
UniProt Synonym Gene Names
FACE1; STE24; FACE-1??[Similar Products]
NCBI Summary for ZMPSTE24
This gene encodes a member of the peptidase M48A family. The encoded protein is a zinc metalloproteinase involved in the two step post-translational proteolytic cleavage of carboxy terminal residues of farnesylated prelamin A to form mature lamin A. Mutations in this gene have been associated with mandibuloacral dysplasia and restrictive dermopathy. [provided by RefSeq, Jul 2008]
UniProt Comments for ZMPSTE24
Proteolytically removes the C-terminal three residues of farnesylated proteins. Acts on lamin A/C.
Research Articles on ZMPSTE24
1. ZMPSTE24 is a downstream effector of IFITM3 and is important for interferon-induced transmembrane antiviral activity.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
